caa a22 4500 445853581 CHVBK 20180317145421.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00204-011-0678-1 doi (NATIONALLICENCE)springer-10.1007/s00204-011-0678-1 Air sampling and determination of vapours and aerosols of bitumen and polycyclic aromatic hydrocarbons in the Human Bitumen Study [Elektronische Daten] [Dietmar Breuer, Jens-Uwe Hahn, Dieter Höber, Christoph Emmel, Uwe Musanke, Reinhold Rühl, Anne Spickenheuer, Monika Raulf-Heimsoth, Rainer Bramer, Albrecht Seidel, Bernd Schilling, Evelyn Heinze, Benjamin Kendzia, Boleslaw Marczynski, Peter Welge, Jürgen Angerer, Thomas Brüning, Beate Pesch] The chemical complexity of emissions from bitumen applications is a challenge in the assessment of exposure. Personal sampling of vapours and aerosols of bitumen was organized in 320 bitumen-exposed workers and 69 non-exposed construction workers during 2001-2008. Area sampling was conducted at 44 construction sites. Area and personal sampling of vapours and aerosols of bitumen showed similar concentrations between 5 and 10mg/m3, while area sampling yielded higher concentrations above the former occupational exposure limit (OEL) of 10mg/m3. The median concentration of personal bitumen exposure was 3.46mg/m3 (inter-quartile range 1.80-5.90mg/m3). Only few workers were exposed above the former OEL. The specificity of the method measuring C-H stretch vibration is limited. This accounts for a median background level of 0.20mg/m³ in non-exposed workers which is likely due to ubiquitous aliphatic hydrocarbons. Further, area measurements of polycyclic aromatic hydrocarbons (PAHs) were taken at 25 construction sites. U.S. EPA PAHs were determined with GC/MS, with the result of a median concentration of 2.47μg/m3 at 15 mastic asphalt worksites associated with vapours and aerosols of bitumen, with a Spearman correlation coefficient of 0.45 (95% CI −0.13 to 0.78). PAH exposure at mastic-asphalt works was higher than at reference worksites (median 0.21μg/m3), but about one order of magnitude lower compared to coke-oven works. For a comparison of concentrations of vapours and aerosols of bitumen and PAHs in asphalt works, differences in sampling and analytical methods must to be taken into account. Springer-Verlag, 2011 Air sampling nationallicence Asphalt nationallicence Bitumen nationallicence Exposure assessment nationallicence Polycyclic aromatic hydrocarbons nationallicence Breuer Dietmar Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA), Sankt Augustin, Germany aut Hahn Jens-Uwe Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA), Sankt Augustin, Germany aut Höber Dieter BG BAU, München and Frankfurt, Germany aut Emmel Christoph BG BAU, München and Frankfurt, Germany aut Musanke Uwe BG BAU, München and Frankfurt, Germany aut Rühl Reinhold BG BAU, München and Frankfurt, Germany aut Spickenheuer Anne Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Raulf-Heimsoth Monika Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Bramer Rainer Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Seidel Albrecht Biochemical Institute for Environmental Carcinogens, Prof. Dr. Gernot Grimmer-Stiftung, Grosshansdorf, Germany aut Schilling Bernd Eurofins GfA GmbH, Hamburg, Germany aut Heinze Evelyn Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Kendzia Benjamin Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Marczynski Boleslaw Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Welge Peter Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Angerer Jürgen Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Brüning Thomas Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Pesch Beate Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut Archives of Toxicology Springer-Verlag 85(2011-06-01), 11-20 0340-5761 85<11 2011 85 204 https://doi.org/10.1007/s00204-011-0678-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00204-011-0678-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Breuer Dietmar Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA), Sankt Augustin, Germany aut NATIONALLICENCE 700 1- Hahn Jens-Uwe Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA), Sankt Augustin, Germany aut NATIONALLICENCE 700 1- Höber Dieter BG BAU, München and Frankfurt, Germany aut NATIONALLICENCE 700 1- Emmel Christoph BG BAU, München and Frankfurt, Germany aut NATIONALLICENCE 700 1- Musanke Uwe BG BAU, München and Frankfurt, Germany aut NATIONALLICENCE 700 1- Rühl Reinhold BG BAU, München and Frankfurt, Germany aut NATIONALLICENCE 700 1- Spickenheuer Anne Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Raulf-Heimsoth Monika Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Bramer Rainer Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Seidel Albrecht Biochemical Institute for Environmental Carcinogens, Prof. Dr. Gernot Grimmer-Stiftung, Grosshansdorf, Germany aut NATIONALLICENCE 700 1- Schilling Bernd Eurofins GfA GmbH, Hamburg, Germany aut NATIONALLICENCE 700 1- Heinze Evelyn Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Kendzia Benjamin Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Marczynski Boleslaw Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Welge Peter Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Angerer Jürgen Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Brüning Thomas Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 700 1- Pesch Beate Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany aut NATIONALLICENCE 773 0- Archives of Toxicology Springer-Verlag 85(2011-06-01), 11-20 0340-5761 85<11 2011 85 204 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer