caa a22 4500 445857463 CHVBK 20180317145432.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10592-010-0172-y doi (NATIONALLICENCE)springer-10.1007/s10592-010-0172-y Genetic structure of Brandt's vole ( Lasiopodomys brandtii ) populations in Inner Mongolia, China, based on microsatellite analysis [Elektronische Daten] [Deng Wang, Yongwang Guo, Dazhao Shi] Brandt's vole (Lasiopodomys brandtii) distribution is discontinuous in Inner Mongolia with some populations isolated from others. Recently, some isolated populations have suffered extinction, and the factors responsible remain elusive. Genetic drift is one of the processes affecting population genetic differentiation, and can play a substantial role in the divergence of small, isolated populations. Using seven microsatellite markers, we genotyped four geographically isolated populations of Brandt's vole, all of which exhibit episodic fluctuations in population density. The results showed a strong genetic differentiation among the geographically distinct populations (total F ST=0.124) and in particular, one population (Zhengxiangbaiqi) was isolated from all others (F ST values were greatest between Zhengxiangbaiqi and other populations). Furthermore, high levels of inbreeding (F IS values ranged from 0.205 to 0.290) within each distinct population suggest that inbreeding has and is likely occurring in Brandt's vole populations. These processes can decrease average individual fitness and consequently increase the risk of extinction of the species. Springer Science+Business Media B.V., 2010 Brandt's vole nationallicence Microsatellite DNA markers nationallicence Genetic differentiation nationallicence Inbreeding nationallicence Wang Deng College of Agronomy and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Haidian District, 100193, Beijing, China aut Guo Yongwang National Agro-tech Extensions and Service Center, 20 Maizidian Avenue, Chaoyang District, 100026, Beijing, China aut Shi Dazhao College of Agronomy and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Haidian District, 100193, Beijing, China aut Conservation Genetics Springer Netherlands 12/3(2011-06-01), 659-667 1566-0621 12:3<659 2011 12 10592 https://doi.org/10.1007/s10592-010-0172-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10592-010-0172-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Deng College of Agronomy and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Haidian District, 100193, Beijing, China aut NATIONALLICENCE 700 1- Guo Yongwang National Agro-tech Extensions and Service Center, 20 Maizidian Avenue, Chaoyang District, 100026, Beijing, China aut NATIONALLICENCE 700 1- Shi Dazhao College of Agronomy and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Haidian District, 100193, Beijing, China aut NATIONALLICENCE 773 0- Conservation Genetics Springer Netherlands 12/3(2011-06-01), 659-667 1566-0621 12:3<659 2011 12 10592 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer