caa a22 4500 445858141 CHVBK 20180317145434.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10592-010-0143-3 doi (NATIONALLICENCE)springer-10.1007/s10592-010-0143-3 The consequences on fitness of equating family contributions: inferences from a drosophila experiment [Elektronische Daten] [Enrique Sánchez-Molano, Aurora García-Dorado] Here we present results of a Drosophila long term experiment where we study the fitness consequences of equating the number of breeding offspring contributed per family (EC) compared to a random contribution (RC) protocol. The EC strategy slows inbreeding and drift. However, it also prevents natural selection on fecundity and limits selection on viability to that occurring within families, and this includes purge against unconditionally deleterious alleles as well as adaptation to captive conditions. We used populations maintained with 5 or 25 single mated pairs, monitored inbreeding and selection intensity, and assayed competitive and non competitive fitness, as well as fecundity and viability components, in lines maintained with or without EC. In the small lines, EC showed modest advantage for viability during the whole experiment and for fitness up to generation 15 while, in the large lines, fitness increased steadily under both strategies, and EC led in the medium term to a slight fitness disadvantage. On the light of recent theory, these results can be explained as the joint consequence of new and standing deleterious mutations undergoing drift, inbreeding and selection and of adaptation to captive conditions. Springer Science+Business Media B.V., 2010 Inbreeding depression nationallicence Purge nationallicence Conservation nationallicence Adaptation to captive conditions nationallicence Fitness components nationallicence Population number nationallicence Sánchez-Molano Enrique Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid, 28040, Madrid, Spain aut García-Dorado Aurora Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid, 28040, Madrid, Spain aut Conservation Genetics Springer Netherlands 12/2(2011-04-01), 343-353 1566-0621 12:2<343 2011 12 10592 https://doi.org/10.1007/s10592-010-0143-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10592-010-0143-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sánchez-Molano Enrique Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid, 28040, Madrid, Spain aut NATIONALLICENCE 700 1- García-Dorado Aurora Departamento de Genética, Facultad de Biología, Universidad Complutense de Madrid, 28040, Madrid, Spain aut NATIONALLICENCE 773 0- Conservation Genetics Springer Netherlands 12/2(2011-04-01), 343-353 1566-0621 12:2<343 2011 12 10592 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer