caa a22 4500 445869860 CHVBK 20180317145508.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s11101-010-9202-0 doi (NATIONALLICENCE)springer-10.1007/s11101-010-9202-0 Anticancer potential of Himalayan plants [Elektronische Daten] [Anjana Bhatia, Saroj Arora, Bikram Singh, Gurveen Kaur, Avinash Nagpal] Plants used in traditional medicine have stood up to the test of time and contributed many novel compounds for preventive and curative medicine to modern science. India is sitting on a gold mine of well recorded and traditionally well practiced knowledge of herbal medicine. Specially, plants growing at high altitude in Himalayan pastures are time-honored sources of health and general well being of local inhabitants. As of today, Himalayan plants are a major contributor to the herbal pharmaceutical industry both of India and other countries. Plants growing at higher altitudes are subjected to an assault of diverse testing situations including higher doses of mutagenic UV-radiation, physiological drought, desiccation and strong winds. Plants interact with stressful environments by physiological adaptation and altering the biochemical profile of plant tissues and producing a spectrum of secondary metabolites. Secondary metabolites are of special interest to scientists because of their unique pharmacophores and medicinal properties. Secondary metabolites like polyphenols, terpenes and alkaloids have been reported to possess antimutagenic and anticancer properties in many studies. The fundamental aspiration of the current review is to divulge the antimutagenic/anticancer potential of five alpine plants used as food or medicine by the populations living at high altitudes. Springer Science+Business Media B.V., 2010 Arnebia euchroma nationallicence Hippophae rhamnoides nationallicence Hypericum perforatum nationallicence Podophyllum hexandrum nationallicence Rheum emodi nationallicence Bhatia Anjana Department of Botany, Hans Raj Mahila Maha Vidyalaya, Jalandhar, India aut Arora Saroj Department of Botanical and Environmental Sciences, Guru Nanak Dev University, 143 005, Amritsar, India aut Singh Bikram Institute of Himalayan Bioresource Technology, 176 061, Palampur, Himachal Pradesh, India aut Kaur Gurveen Department of Botanical and Environmental Sciences, Guru Nanak Dev University, 143 005, Amritsar, India aut Nagpal Avinash Department of Botanical and Environmental Sciences, Guru Nanak Dev University, 143 005, Amritsar, India aut Phytochemistry Reviews Springer Netherlands 10/3(2011-09-01), 309-323 1568-7767 10:3<309 2011 10 11101 https://doi.org/10.1007/s11101-010-9202-0 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11101-010-9202-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bhatia Anjana Department of Botany, Hans Raj Mahila Maha Vidyalaya, Jalandhar, India aut NATIONALLICENCE 700 1- Arora Saroj Department of Botanical and Environmental Sciences, Guru Nanak Dev University, 143 005, Amritsar, India aut NATIONALLICENCE 700 1- Singh Bikram Institute of Himalayan Bioresource Technology, 176 061, Palampur, Himachal Pradesh, India aut NATIONALLICENCE 700 1- Kaur Gurveen Department of Botanical and Environmental Sciences, Guru Nanak Dev University, 143 005, Amritsar, India aut NATIONALLICENCE 700 1- Nagpal Avinash Department of Botanical and Environmental Sciences, Guru Nanak Dev University, 143 005, Amritsar, India aut NATIONALLICENCE 773 0- Phytochemistry Reviews Springer Netherlands 10/3(2011-09-01), 309-323 1568-7767 10:3<309 2011 10 11101 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer