caa a22 4500 445869933 CHVBK 20180317145508.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s11101-010-9180-2 doi (NATIONALLICENCE)springer-10.1007/s11101-010-9180-2 Control of plant parasitic nematodes with active saponins and biomass from Medicago sativa [Elektronische Daten] [T. D'Addabbo, T. Carbonara, P. Leonetti, V. Radicci, A. Tava, P. Avato] Medicago sativa L., alfalfa, is the most known plant species within the Medicago genus. The plant has been extensively studied for its content of saponins, mainly consisting of triterpene glycosides of medicagenic acid, possessing several biological properties including a biocidal activity on different soil microorganisms. Phytoparasitic nematodes are responsible for heavy economic damages to numerous agricultural crops and, due to their large distribution, they are among the most difficult crop pests to control. Attention on environmental safety and human and animal health has led to the progressive dismission of many synthetic formulations for the control of those pests and to the search of alternative strategies, including the use of natural metabolites from plants. Saponins from M. sativa may be good candidates for natural nematicide formulations, as in our in vitro studies the saponin mixtures from M. sativa tissues have been found effective in vitro against the virus-vector nematode Xiphinema index, the root-knot nematode Meloidogyne incognita and the potato cyst parasite, Globodera rostochiensis. A structure-activity relationship among saponins and related prosapogenins and sapogenin, respectively, has also been analyzed. The nematicidal efficacy differed among the three assayed nematode species, G. rostochiensis being the most susceptible to the active compounds from alfalfa. The in vitro results were also confirmed by experiments in potting mixes infested by M. incognita or G. rostochiensis and amended with dry top and root material from M. sativa, and in field trials on M. incognita and carrot cyst nematode Heterodera carotae with M. sativa pelleted meal. All amendments reduced root and soil population densities of target nematode species compared to non-treated and chemical controls, with a general improvement of plant growth and yield performances. Springer Science+Business Media B.V., 2010 Alfalfa nationallicence Biocide nationallicence Medicagenic acid nationallicence Phytoparasite nematodes nationallicence Sapogenins nationallicence D'Addabbo T. Istituto per la Protezione delle Piante, CNR, Via Amendola 165/a, 70126, Bari, Italy aut Carbonara T. Dipartimento Farmaco-Chimico, Universitá di Bari, Via Orabona 4, 70125, Bari, Italy aut Leonetti P. Istituto per la Protezione delle Piante, CNR, Via Amendola 165/a, 70126, Bari, Italy aut Radicci V. Istituto per la Protezione delle Piante, CNR, Via Amendola 165/a, 70126, Bari, Italy aut Tava A. C.R.A-FLC Centro di Ricerca per le Produzioni Foraggere e Lattiero-Casearie, V.le Piacenza 29, 26900, Lodi, Italy aut Avato P. Dipartimento Farmaco-Chimico, Universitá di Bari, Via Orabona 4, 70125, Bari, Italy aut Phytochemistry Reviews Springer Netherlands 10/4(2011-12-01), 503-519 1568-7767 10:4<503 2011 10 11101 https://doi.org/10.1007/s11101-010-9180-2 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11101-010-9180-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- D'Addabbo T. Istituto per la Protezione delle Piante, CNR, Via Amendola 165/a, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Carbonara T. Dipartimento Farmaco-Chimico, Universitá di Bari, Via Orabona 4, 70125, Bari, Italy aut NATIONALLICENCE 700 1- Leonetti P. Istituto per la Protezione delle Piante, CNR, Via Amendola 165/a, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Radicci V. Istituto per la Protezione delle Piante, CNR, Via Amendola 165/a, 70126, Bari, Italy aut NATIONALLICENCE 700 1- Tava A. C.R.A-FLC Centro di Ricerca per le Produzioni Foraggere e Lattiero-Casearie, V.le Piacenza 29, 26900, Lodi, Italy aut NATIONALLICENCE 700 1- Avato P. Dipartimento Farmaco-Chimico, Universitá di Bari, Via Orabona 4, 70125, Bari, Italy aut NATIONALLICENCE 773 0- Phytochemistry Reviews Springer Netherlands 10/4(2011-12-01), 503-519 1568-7767 10:4<503 2011 10 11101 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer