caa a22 4500 445870087 CHVBK 20180317145509.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s11101-010-9175-z doi (NATIONALLICENCE)springer-10.1007/s11101-010-9175-z An overview of NMR-based metabolomics to identify secondary plant compounds involved in host plant resistance [Elektronische Daten] [Kirsten Leiss, Young Choi, Robert Verpoorte, Peter Klinkhamer] Secondary metabolites provide a potential source for the generation of host plant resistance and development of biopesticides. This is especially important in view of the rapid and vast spread of agricultural and horticultural pests worldwide. Multiple pests control tactics in the framework of an integrated pest management (IPM) programme are necessary. One important strategy of IPM is the use of chemical host plant resistance. Up to now the study of chemical host plant resistance has, for technical reasons, been restricted to the identification of single compounds applying specific chemical analyses adapted to the compound in question. In biological processes however, usually more than one compound is involved. Metabolomics allows the simultaneous detection of a wide range of compounds, providing an immediate image of the metabolome of a plant. One of the most universally used metabolomic approaches comprises nuclear magnetic resonance spectroscopy (NMR). It has been NMR which has been applied as a proof of principle to show that metabolomics can constitute a major advancement in the study of host plant resistance. Here we give an overview on the application of NMR to identify candidate compounds for host plant resistance. We focus on host plant resistance to western flower thrips (Frankliniella occidentalis) which has been used as a model for different plant species. The Author(s), 2010 Eco-metabolomic approach nationallicence Host plant resistance nationallicence NMR metabolomics nationallicence Secondary plant metabolites nationallicence Thrips ( Frankliniella occidentalis ) nationallicence Leiss Kirsten Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut Choi Young Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut Verpoorte Robert Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut Klinkhamer Peter Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut Phytochemistry Reviews Springer Netherlands 10/2(2011-06-01), 205-216 1568-7767 10:2<205 2011 10 11101 https://doi.org/10.1007/s11101-010-9175-z text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11101-010-9175-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Leiss Kirsten Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Choi Young Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Verpoorte Robert Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Klinkhamer Peter Section Plant Ecology and Metabolomics, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands aut NATIONALLICENCE 773 0- Phytochemistry Reviews Springer Netherlands 10/2(2011-06-01), 205-216 1568-7767 10:2<205 2011 10 11101 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer