caa a22 4500 445874899 CHVBK 20180317145524.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s10593-011-0702-7 doi (NATIONALLICENCE)springer-10.1007/s10593-011-0702-7 Synthesis and hydrazinolysis of β-(1,3,4-oxadiazol-2-yl)pyridines [Elektronische Daten] [O. Nesterova, A. Pugachova, M. Voevudsky, O. Krischik, V. Musatov] Cyclization of the hydrazide of 5-ethoxycarbonyl-2,6-dimethylpyridine-3-carboxylic acid by acylation with aromatic or aliphatic acid chlorides with subsequent boiling in POCl3 or heating in orthoformic acid gave the corresponding ethyl 2,6-dimethyl-5-(5-R-1,3,4-oxadiazol-2-yl)pyridine-3-carboxylate. The cyclization of the reaction products with hydrazine hydrate has been studied. Cyclization of the dihydrazide of 2,6-dimethyl-3,5-pyridinedicarboxylic acid under analogous conditions gave only 3,5-bis-(5-R-1,3,4-oxadiazol-2-yl)-2,6-dimethylpyridines, containing R = 2-FC6H4, H. Springer Science+Business Media, Inc., 2011 hydrazide nationallicence hydrazine nationallicence nicotinic acid nationallicence 1,3,4-oxadiazole nationallicence aromatic acid chlorides nationallicence Nesterova O. O. Gonchar Dnepropetrovsk National University, 49010, Dnepropetrovsk, Ukraine aut Pugachova A. O. Gonchar Dnepropetrovsk National University, 49010, Dnepropetrovsk, Ukraine aut Voevudsky M. Ukrainian State University of Chemical Engineering, 49005, Dnepropetrovsk, Ukraine aut Krischik O. Ukrainian State University of Chemical Engineering, 49005, Dnepropetrovsk, Ukraine aut Musatov V. Institute for Single Crystals, National Academy of Sciences of Ukraine, 61001, Kharkiv, Ukraine aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 46/12(2011-03-01), 1520-1526 0009-3122 46:12<1520 2011 46 10593 https://doi.org/10.1007/s10593-011-0702-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0702-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nesterova O. O. Gonchar Dnepropetrovsk National University, 49010, Dnepropetrovsk, Ukraine aut NATIONALLICENCE 700 1- Pugachova A. O. Gonchar Dnepropetrovsk National University, 49010, Dnepropetrovsk, Ukraine aut NATIONALLICENCE 700 1- Voevudsky M. Ukrainian State University of Chemical Engineering, 49005, Dnepropetrovsk, Ukraine aut NATIONALLICENCE 700 1- Krischik O. Ukrainian State University of Chemical Engineering, 49005, Dnepropetrovsk, Ukraine aut NATIONALLICENCE 700 1- Musatov V. Institute for Single Crystals, National Academy of Sciences of Ukraine, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 46/12(2011-03-01), 1520-1526 0009-3122 46:12<1520 2011 46 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer