caa a22 4500 445875658 CHVBK 20180317145527.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10593-011-0726-z doi (NATIONALLICENCE)springer-10.1007/s10593-011-0726-z Synthesis and pharmacological activities of some dibenzopyrazolocinnolines and dibenzopyridazinoquinoxalines [Elektronische Daten] [A. Amer, A. El-Farargy, N. Yousif, A. Fayed] Derivatives of three new classes of heterocyclic compounds have been synthesized. The first class comprises the synthesis of pyrimidino- and imidazolopyrazolopyridazine using 11H-dibenzo[f,h]pyrazolo[3,4-c]-cinnoline-13-amine. The second class involves the synthesis of triazine derivatives using 11H-dibenzo-[f,h]pyrazolo[3,4-c]cinnoline-13-diazonium chloride. The third class deals with the synthesis of polycyclic compounds using dibenzo[f,h]pyridazino[4,5-b]quinoxaline-10,13-diamine. The pharmacological screening has shown that several of these compounds have good antiparkinsonian activities comparable to Benzatropine. The detailed synthesis, spectroscopic data, and pharmacological properties are reported. Springer Science+Business Media, Inc., 2011 pyridazine nationallicence pyrimidine nationallicence triazine nationallicence antiparkinsonian activity nationallicence Amer A. Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt aut El-Farargy A. Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt aut Yousif N. National Research Center, Photochemistry Department, Cairo, Dokki, Egypt aut Fayed A. National Research Center, Photochemistry Department, Cairo, Dokki, Egypt aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/1(2011-04-01), 101-107 0009-3122 47:1<101 2011 47 10593 https://doi.org/10.1007/s10593-011-0726-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0726-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Amer A. Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- El-Farargy A. Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- Yousif N. National Research Center, Photochemistry Department, Cairo, Dokki, Egypt aut NATIONALLICENCE 700 1- Fayed A. National Research Center, Photochemistry Department, Cairo, Dokki, Egypt aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/1(2011-04-01), 101-107 0009-3122 47:1<101 2011 47 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer