caa a22 4500 445875844 CHVBK 20180317145527.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10593-011-0824-y doi (NATIONALLICENCE)springer-10.1007/s10593-011-0824-y Reactions of 5-(het)aryl-1-ethyl-2(1 H )-pyrazinones with terminal arylacetylenes promoted by microwave radiation [Elektronische Daten] [E. Verbitskiy, E. Cheprakova, P. Slepuhin, M. Pervova, M. Samorukova, O. Zabelina, G. Rusinov, V. Charushin] The reaction of 5-(het)aryl-1-ethyl-2(1H)-pyrazinones with terminal arylacetylenes, leading to a mixture of two isomeric 4-aryl- and 5-aryl-substituted 2(1H)-pyridones has been investigated. The regioselectivity of this reaction has been shown on the basis of reaction mixtures study by chromato-mass spectrometry. A crystallographic investigation of the synthesized 2(1H)-pyridones and also a forecast of their potential biological activity have been carried out. Springer Science+Business Media, Inc., 2011 σH-adducts nationallicence arylacetylenes nationallicence 1,2-dihydropyrazines nationallicence ionic liquid nationallicence 2(1H)-pyrazinones nationallicence 2(1H)-pyridones nationallicence microwave radiation nationallicence Verbitskiy E. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Cheprakova E. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Slepuhin P. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Pervova M. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Samorukova M. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Zabelina O. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Rusinov G. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Charushin V. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/6(2011-09-01), 710-718 0009-3122 47:6<710 2011 47 10593 https://doi.org/10.1007/s10593-011-0824-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0824-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Verbitskiy E. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Cheprakova E. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Slepuhin P. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Pervova M. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Samorukova M. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Zabelina O. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Rusinov G. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Charushin V. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi/20 Akademicheskaya St, 620041, Yekaterinburg, Russia aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/6(2011-09-01), 710-718 0009-3122 47:6<710 2011 47 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer