caa a22 4500 445875984 CHVBK 20180317145528.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10593-011-0885-y doi (NATIONALLICENCE)springer-10.1007/s10593-011-0885-y Synthesis of 2-hetaryl-2-(tetrahydrofuran-2-ylidene)acetonitriles [Elektronische Daten] [O. Khilya, T. Volovnenko, A. Turov, R. Zubatyuk, O. Shishkin, Yu. Volovenko] The reaction of azolylacetonitriles with γ-chlorobutyryl chlorides gave the corresponding 2-(1-R-1,3-di- hydro-2H-benzimidazol-2-ylidene)-, 2-(1,3-benzothiazol-2-ylidene)-, and 6-chloro-2-(4-methylthiazol-2-ylidene)-3-oxohexanenitriles. A study of the intramolecular cyclization of 2-(quinazolin-2-ylidene)-3-oxo-6-hexanenitriles and -heptanenitriles has led to the development of an efficient method for the preparation of 2-(quinazolin-2-yl)-2-(tetrahydrofuran-2-ylidene)acetonitriles. The (Z,E)-isomerism of the synthesized 2-hetaryl-2-(tetrahydrofuran-2-ylidene)acetonitriles was studied. Springer Science+Business Media, Inc., 2011 benzimidazolylacetonitrile nationallicence 2-(1-R-benzimidazol-2-yl)-2-(tetrahydrofuran-2-ylidene)aceto- nitrile nationallicence benzothiazolylacetonitrile nationallicence 2-(1,3-benzothiazol-2-ylidene)-6-chloro-3-oxohexanenitrile nationallicence 2-(1,3-benzo- thiazol-2-yl)-2-(tetrahydrofuran-2-ylidene)acetonitrile nationallicence 6-chloro-2-(1-R-1,3-dihydro-2H-benzimidazol-2-ylidene)-3-oxo-hexanenitrile nationallicence 6-chloro-2-(4-methylthiazol-2-ylidene)-3-oxohexanenitrile nationallicence 2-(4-methyl-thiazol-2-yl)-2-(tetrahydrofuran-2-ylidene)acetonitrile nationallicence 4-oxo-3,4-dihydroquinazolylacetonitrile nationallicence intramole- cular cyclization nationallicence Khilya O. Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut Volovnenko T. Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut Turov A. Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut Zubatyuk R. Institute for Single Crystals, 60 Lenin Ave., 310001, Kharkiv, Ukraine aut Shishkin O. Institute for Single Crystals, 60 Lenin Ave., 310001, Kharkiv, Ukraine aut Volovenko Yu Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/9(2011-12-01), 1141-1154 0009-3122 47:9<1141 2011 47 10593 https://doi.org/10.1007/s10593-011-0885-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0885-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khilya O. Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Volovnenko T. Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Turov A. Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Zubatyuk R. Institute for Single Crystals, 60 Lenin Ave., 310001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Shishkin O. Institute for Single Crystals, 60 Lenin Ave., 310001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Volovenko Yu Taras Shevchenko Kyiv National University, 64 Volodymyrska St., 01601, Kyiv, Ukraine aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/9(2011-12-01), 1141-1154 0009-3122 47:9<1141 2011 47 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer