caa a22 4500 445876255 CHVBK 20180317145528.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10593-011-0763-7 doi (NATIONALLICENCE)springer-10.1007/s10593-011-0763-7 Condensed isoquinolines. 37.* Heterocyclization using 3-(arylamino)- and 3-(hetarylamino)isoquinolin-1(2H)-ones [Elektronische Daten] [L. Potikha, R. Gutsul, A. Plaskon, V. Kovtunenko, A. Tolmachev] The reaction of 3-NHR-isoquinolin-1(2H)-ones (R = Ar) with aromatic aldehydes in the presence of Me3SiCl or in acetic acid leads to the formation of derivatives of dibenzo[b,f][1, 8]naphthyridin-5(6H)- one and benzo[f]isoquino[3,4-b][1, 8]naphthyridine-5,9(6H,7H)-dione. The reaction for R = Het in the presence of Me3SiCl gives derivatives of 5H-pyrido[1',2':1,2]pyrimido[4,5-c]isoquinolin-5-one, benzo[f]isoquinoline[3,4-b][1,8]naphthyridine-5,9[6H,7H]-dione, and derivatives of new heterocyclic systems, 5H-pyrazino[1',2':1,2]pyrimido[4,5-c]isoquinolin-5-one, 5H-[1,3]thiazolo[3',2':1,2]pyrimido- [4,5-c]isoquinolin-5-one, 5-H-benzo[f]pyrazolo[3,4-b][1,8]naphthyridin-5-one, and isoquino[3,4-b]- [1,5]naphthyridin-5(6H)-one. The effect of the structure of substituent R and nature of the substituent in the benzaldehydes on the structure of the reaction products was studied. Springer Science+Business Media, Inc., 2011 3-aminoisocarbostyryl nationallicence benzo[ f ]isoquino[3,4- b ][1,8]naphthyridine nationallicence benzo[ f ]pyrazolo[3,4- b ]- [1,8]naphthyridine nationallicence dibenzo[ b,f ][1,8]naphthyridine nationallicence isoquino[3,4- b ][1,5]naphthyridine nationallicence pyrazino[1',2':1,2]- pyrimido[4,5- c ]isoquinoline nationallicence pyrido[1',2':1,2]pyrimido[4,5- c ]isoquinoline nationallicence [1,3]thiazolo[3',2':1,2]pyrimido- [4,5- c ]isoquinoline nationallicence Potikha L. Taras Shevchenko National University, 64 Volodymirska St., 01033, Kyiv, Ukraine aut Gutsul R. UkrOrgSynthesis Ltd., 29 Shchorsa St., 01133, Kyiv, Ukraine aut Plaskon A. Enamine, 23 Alexandra Matrosova St., 01133, Kyiv, Ukraine aut Kovtunenko V. Taras Shevchenko National University, 64 Volodymirska St., 01033, Kyiv, Ukraine aut Tolmachev A. Enamine, 23 Alexandra Matrosova St., 01133, Kyiv, Ukraine aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/3(2011-06-01), 342-354 0009-3122 47:3<342 2011 47 10593 https://doi.org/10.1007/s10593-011-0763-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0763-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Potikha L. Taras Shevchenko National University, 64 Volodymirska St., 01033, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Gutsul R. UkrOrgSynthesis Ltd., 29 Shchorsa St., 01133, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Plaskon A. Enamine, 23 Alexandra Matrosova St., 01133, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Kovtunenko V. Taras Shevchenko National University, 64 Volodymirska St., 01033, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Tolmachev A. Enamine, 23 Alexandra Matrosova St., 01133, Kyiv, Ukraine aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/3(2011-06-01), 342-354 0009-3122 47:3<342 2011 47 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer