caa a22 4500 445876441 CHVBK 20180317145529.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s10593-011-0787-z doi (NATIONALLICENCE)springer-10.1007/s10593-011-0787-z Synthesis of some N-alkylated 1,2,4-triazoles, 1,3,4-oxadiazoles, and 1,3,4-thiadiazoles based on N-(furan-2-yl-methylidene)-4,6-dimethyl-1H-pyrazolo-[3,4- b ]pyridine-3-amine [Elektronische Daten] [F. El-Essawy, S. Rady] N-(Furan-2-ylmethylidene)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-3-amine was prepared and alkyla- ted with the corresponding halo compounds to afford N-alkylated products. 2-[3-(Furan-2-ylmethy- lideneamino)-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-1-yl]acetohydrazide was converted into the key intermediate thiosemicarbazide, which undergoes cyclization reactions under acidic and basic conditi- ons to give 1,2,4-triazole, 1,3,4-oxadiazole, and 1,3,4-thiadiazole derivatives. Condensation of the hyd- razide with monosaccharide aldoses gave the corresponding sugar hydrazones, which on treatment with acetic anhydride readily undergo cyclization reaction to afford oxadiazoline derivatives. Springer Science+Business Media, Inc., 2011 aldoses nationallicence 1,3,4-oxadiazole nationallicence pyrazolopyridine nationallicence 1,3,4-thiadiazole nationallicence thiosemicarbazide nationallicence 1,2,4-triazole nationallicence cyclization nationallicence El-Essawy F. Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt aut Rady S. Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/4(2011-07-01), 497-506 0009-3122 47:4<497 2011 47 10593 https://doi.org/10.1007/s10593-011-0787-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0787-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- El-Essawy F. Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt aut NATIONALLICENCE 700 1- Rady S. Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/4(2011-07-01), 497-506 0009-3122 47:4<497 2011 47 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer