caa a22 4500 445876980 CHVBK 20180317145530.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10593-011-0801-5 doi (NATIONALLICENCE)springer-10.1007/s10593-011-0801-5 Synthesis, spectral analysis, and in vitro microbiological evaluation of ethyl 7,9-diaryl-1, 4-diazaspiro[4.5]dec-9-ene-6- carboxylates as a new class of antibacterial and antifungal agents [Elektronische Daten] [J. Thanusu, V. Kanagarajan, M. Gopalakrishnan] A series of novel ethyl 7,9-diaryl-1,4-diazaspiro[4.5]dec-9-ene-6-carboxylates was synthesized by the reaction of ethyl 4,6-diaryl-2-oxocyclohex-3-ene-1-carboxylates with ethylenediamine in the presence of p-toluenesulfonic acid without a solvent under focused microwave irradiation. The title compounds were screened for their antimicrobial activities against a spectrum of clinically isolated microorganisms. Springer Science+Business Media, Inc., 2011 ethyl 7,9-diaryl-1,4-diazaspiro[4.5]dec-9-ene-6-carboxylates nationallicence ethylenediamine nationallicence p -toluene-sulfonic acid nationallicence antibacterial activity nationallicence antifungal activity nationallicence Thanusu J. Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Nagar-608 002, Annamalai, Tamil Nadu, India aut Kanagarajan V. Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Nagar-608 002, Annamalai, Tamil Nadu, India aut Gopalakrishnan M. Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Nagar-608 002, Annamalai, Tamil Nadu, India aut Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/5(2011-08-01), 575-583 0009-3122 47:5<575 2011 47 10593 https://doi.org/10.1007/s10593-011-0801-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10593-011-0801-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Thanusu J. Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Nagar-608 002, Annamalai, Tamil Nadu, India aut NATIONALLICENCE 700 1- Kanagarajan V. Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Nagar-608 002, Annamalai, Tamil Nadu, India aut NATIONALLICENCE 700 1- Gopalakrishnan M. Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University, Nagar-608 002, Annamalai, Tamil Nadu, India aut NATIONALLICENCE 773 0- Chemistry of Heterocyclic Compounds Springer US; http://www.springer-ny.com 47/5(2011-08-01), 575-583 0009-3122 47:5<575 2011 47 10593 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer