caa a22 4500 445877650 CHVBK 20180317145532.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s11187-011-9339-2 doi (NATIONALLICENCE)springer-10.1007/s11187-011-9339-2 Candidate gene studies and the quest for the entrepreneurial gene [Elektronische Daten] [Matthijs van der Loos, Philipp Koellinger, Patrick Groenen, Cornelius Rietveld, Fernando Rivadeneira, Frank van Rooij, André Uitterlinden, Albert Hofman, A. Thurik] Candidate gene studies of human behavior are gaining interest in economics and entrepreneurship research. Performing and interpreting these studies is not straightforward because the selection of candidates influences the interpretation of the results. As an example, Nicolaou et al. (Small Bus Econ 36:151-155, 2011) report a significant association between a common genetic variant in the DRD3 gene and the tendency to be an entrepreneur. We fail to replicate this finding using a much larger, independent dataset. In addition, we discuss the candidate gene approach and give suggestions to avoid the publication of false positives. The Author(s), 2011 Genetics nationallicence Entrepreneurship nationallicence Genome-wide association study nationallicence Candidate gene study nationallicence van der Loos Matthijs Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut Koellinger Philipp Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut Groenen Patrick Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut Rietveld Cornelius Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut Rivadeneira Fernando Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut van Rooij Frank Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut Uitterlinden André Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut Hofman Albert Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut Thurik A. Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut Small Business Economics Springer US; http://www.springer-ny.com 37/3(2011-10-01), 269-275 0921-898X 37:3<269 2011 37 11187 https://doi.org/10.1007/s11187-011-9339-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11187-011-9339-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van der Loos Matthijs Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Koellinger Philipp Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Groenen Patrick Econometric Institute, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Rietveld Cornelius Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Rivadeneira Fernando Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- van Rooij Frank Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Uitterlinden André Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Hofman Albert Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Thurik A. Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands aut NATIONALLICENCE 773 0- Small Business Economics Springer US; http://www.springer-ny.com 37/3(2011-10-01), 269-275 0921-898X 37:3<269 2011 37 11187 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer