caa a22 4500 445878215 CHVBK 20180317145534.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s11030-010-9237-6 doi (NATIONALLICENCE)springer-10.1007/s11030-010-9237-6 Expanding cyclitol structural diversity by biocatalysis and metalocatalysis. A click chemistry approach [Elektronische Daten] [Victoria de la Sovera, Ana Bellomo, Jesus Pena, David Gonzalez, Hélio Stefani] The palladium catalyzed cross-coupling reaction of phenyltrifluoroborate with a chemoenzymatically derived bromoazidoconduritol, combined with 1,3-dipolar cycloaddition, with a variety of alkynes is described. Fourteen new compounds were synthesized in moderate to good yields. The click chemistry reaction can be effected by using sodium ascorbate and CuSO4 · 5H2O as catalyst in toluene-H2O at room temperature. Springer Science+Business Media B.V., 2010 Organotrifloroborates nationallicence Suzuki-Miyaura nationallicence Click chemistry nationallicence Chemoenzymatic synthesis nationallicence de la Sovera Victoria Departamento de Química Orgánica, Facultad de Química, UdelaR, Montevideo, Uruguay aut Bellomo Ana Departamento de Química Orgánica, Facultad de Química, UdelaR, Montevideo, Uruguay aut Pena Jesus Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, SP, Brazil aut Gonzalez David Departamento de Química Orgánica, Facultad de Química, UdelaR, Montevideo, Uruguay aut Stefani Hélio Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, SP, Brazil aut Molecular Diversity Springer Netherlands 15/1(2011-02-01), 163-172 1381-1991 15:1<163 2011 15 11030 https://doi.org/10.1007/s11030-010-9237-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11030-010-9237-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de la Sovera Victoria Departamento de Química Orgánica, Facultad de Química, UdelaR, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Bellomo Ana Departamento de Química Orgánica, Facultad de Química, UdelaR, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Pena Jesus Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, SP, Brazil aut NATIONALLICENCE 700 1- Gonzalez David Departamento de Química Orgánica, Facultad de Química, UdelaR, Montevideo, Uruguay aut NATIONALLICENCE 700 1- Stefani Hélio Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, SP, Brazil aut NATIONALLICENCE 773 0- Molecular Diversity Springer Netherlands 15/1(2011-02-01), 163-172 1381-1991 15:1<163 2011 15 11030 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer