caa a22 4500 445878282 CHVBK 20180317145534.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s11030-010-9266-1 doi (NATIONALLICENCE)springer-10.1007/s11030-010-9266-1 Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives [Elektronische Daten] [Yogesh Pedgaonkar, Mariam Degani, Radhakrishnan Iyer] With the emergence of high throughput screening of bioactive molecules, there is constant need for the development of new strategies for diversity-oriented synthesis. We describe here a novel one-pot multicomponent reaction for the synthesis of uracil derivatives using easily available starting materials. This new synthetic strategy provides easy access to diverse uracil derivatives in moderate to good yields. Graphical Abstract: Springer Science+Business Media B.V., 2010 Multicomponent reaction nationallicence Carbonylation nationallicence Cyclization nationallicence 5-cyanouracil nationallicence Triphosgene nationallicence MCR nationallicence Pedgaonkar Yogesh Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, N. Parekh Marg, Matunga, 400019, Mumbai, India aut Degani Mariam Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, N. Parekh Marg, Matunga, 400019, Mumbai, India aut Iyer Radhakrishnan Spring Bank Pharmaceuticals, Inc., 01757, Milford, MA, USA aut Molecular Diversity Springer Netherlands 15/1(2011-02-01), 263-267 1381-1991 15:1<263 2011 15 11030 https://doi.org/10.1007/s11030-010-9266-1 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11030-010-9266-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pedgaonkar Yogesh Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, N. Parekh Marg, Matunga, 400019, Mumbai, India aut NATIONALLICENCE 700 1- Degani Mariam Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, N. Parekh Marg, Matunga, 400019, Mumbai, India aut NATIONALLICENCE 700 1- Iyer Radhakrishnan Spring Bank Pharmaceuticals, Inc., 01757, Milford, MA, USA aut NATIONALLICENCE 773 0- Molecular Diversity Springer Netherlands 15/1(2011-02-01), 263-267 1381-1991 15:1<263 2011 15 11030 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer