caa a22 4500 445878681 CHVBK 20180317145535.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s11030-011-9302-9 doi (NATIONALLICENCE)springer-10.1007/s11030-011-9302-9 New one-pot synthesis of spiro[furo[2,3- d ]pyrimidine-6,5′-pyrimidine]pentaones and their sulfur analogues [Elektronische Daten] [Mohammad Jalilzadeh, Nader Noroozi Pesyan, Fereshteh Rezaee, Saeed Rastgar, Yaser Hosseini, Ertan Şahin] Reaction of barbituric acid (BA), 1,3-dimethyl barbituric acid (DMBA) and 2-thiobarbituric acid (TBA) with cyanogen bromide and various aldehydes in presence of triethylamine afforded a new class of heterocyclic stable 5-alkyl and/or 5-aryl-1H, 1′H-spiro[furo[2,3-d]pyrimidine-6,5′-pyrimidine]2,2′,4,4′,6′(3H,3′H,5H)-pentaones which are dimeric forms of barbiturate (uracil and thiouracil derivatives) at 0°C to ambient temperatures. Structure elucidation is proved by X-ray crystallography, 1H NMR, 13C NMR, FT-IR, CHN and mass analyses techniques. Mechanisms of the formations are discussed. Springer Science+Business Media B.V., 2011 Barbituric acid nationallicence Spiro[furo[2,3- d ]pyrimidine nationallicence Cyanogen bromide nationallicence Uracil nationallicence Thiouracil nationallicence Jalilzadeh Mohammad Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut Noroozi Pesyan Nader Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut Rezaee Fereshteh Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut Rastgar Saeed Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut Hosseini Yaser Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut Şahin Ertan Department of Chemistry, Faculty of Science, Atatürk University, 25240, Erzurum, Turkey aut Molecular Diversity Springer Netherlands 15/3(2011-08-01), 721-731 1381-1991 15:3<721 2011 15 11030 https://doi.org/10.1007/s11030-011-9302-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11030-011-9302-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jalilzadeh Mohammad Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut NATIONALLICENCE 700 1- Noroozi Pesyan Nader Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut NATIONALLICENCE 700 1- Rezaee Fereshteh Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut NATIONALLICENCE 700 1- Rastgar Saeed Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut NATIONALLICENCE 700 1- Hosseini Yaser Department of Chemistry, Faculty of Science, Urmia University, 57159, Urmia, Iran aut NATIONALLICENCE 700 1- Şahin Ertan Department of Chemistry, Faculty of Science, Atatürk University, 25240, Erzurum, Turkey aut NATIONALLICENCE 773 0- Molecular Diversity Springer Netherlands 15/3(2011-08-01), 721-731 1381-1991 15:3<721 2011 15 11030 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer