caa a22 4500 445879114 CHVBK 20180317145536.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s11030-010-9270-5 doi (NATIONALLICENCE)springer-10.1007/s11030-010-9270-5 One-pot microwave-assisted protocol for the synthesis of substituted 2-amino-1 H -imidazoles [Elektronische Daten] [D. Ermolat'ev, B. Savaliya, A. Shah, E. Van der Eycken] An efficient microwave-assisted one-pot two-step protocol was developed for the construction of disubstituted 2-amino-1H-imidazoles. This process involves the sequential formation of 2,3-dihydro-2-hydroxyimidazo[1,2-a]pyrimidinium salts from readily available 2-aminopyrimidines and α-bromoketones, followed by cleavage of the pyrimidine ring with hydrazine. Graphical abstract: Springer Science+Business Media B.V., 2010 Heterocycles nationallicence 2-Aminoimidazoles nationallicence Microwave-assisted synthesis nationallicence Ring opening nationallicence Rearrangement nationallicence Ermolat'ev D. Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium aut Savaliya B. Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium aut Shah A. Department of Chemistry, Saurashtra University, 360 005, Rajkot, Gujarat, India aut Van der Eycken E. Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium aut Molecular Diversity Springer Netherlands 15/2(2011-05-01), 491-496 1381-1991 15:2<491 2011 15 11030 https://doi.org/10.1007/s11030-010-9270-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11030-010-9270-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ermolat'ev D. Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium aut NATIONALLICENCE 700 1- Savaliya B. Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium aut NATIONALLICENCE 700 1- Shah A. Department of Chemistry, Saurashtra University, 360 005, Rajkot, Gujarat, India aut NATIONALLICENCE 700 1- Van der Eycken E. Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Leuven, Belgium aut NATIONALLICENCE 773 0- Molecular Diversity Springer Netherlands 15/2(2011-05-01), 491-496 1381-1991 15:2<491 2011 15 11030 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer