caa a22 4500 445879386 CHVBK 20180317145537.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00604-010-0499-6 doi (NATIONALLICENCE)springer-10.1007/s00604-010-0499-6 Electrochemical oxidation behavior of guanosine-5´-monophosphate on a glassy carbon electrode modified with a composite film of graphene and multi-walled carbon nanotubes, and its amperometric determination [Elektronische Daten] [Huanshun Yin, Yunlei Zhou, Qiang Ma, Tao Liu, Shiyun Ai, Lusheng Zhu] The electrochemical oxidation of guanosine-5′-monophosphate (GMP) was studied with a glassy carbon electrode modified with a composite made from graphene and multi-walled carbon nanotubes. GMP undergoes an irreversible oxidation process at an oxidation peak potential of 987mV in phosphate buffer solution. Compared to other electrodes, the oxidation peak current of GMP with this electrode was significantly increased, and the corresponding oxidation peak potential negatively shifted, thereby indicating that the modified material exhibited electrochemical catalytic activity towards GMP. Chronocoulometry demonstrates that the material also effectively increases the surface area of the electrode and increases the amount of GMP adsorbed. Under the optimum conditions, the oxidation current is proportional to the GMP concentration in the range from 0.1 to 59.7μM with a correlation coefficient of 0.9991. The detection limit is 0.025μM (at S/N = 3). Figure We have developed an electrochemical method for sensitive determination of guanosine-5'-monophosphate (1) based on graphene and multi-walled carbon nanotubes modified glassy carbon electrode by amperometry. Springer-Verlag, 2010 Graphene nationallicence Multi-walled carbon nanotube nationallicence Guanosine-5´-monophosphate nationallicence Electrochemical oxidation nationallicence Amperometric determination nationallicence Yin Huanshun College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut Zhou Yunlei College of Life Science, Beijing Normal University, 100875, Beijing, China aut Ma Qiang College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut Liu Tao College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut Ai Shiyun College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut Zhu Lusheng College of Resources and Environment, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut Microchimica Acta Springer Vienna 172/3-4(2011-03-01), 343-349 0026-3672 172:3-4<343 2011 172 604 https://doi.org/10.1007/s00604-010-0499-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-010-0499-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yin Huanshun College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut NATIONALLICENCE 700 1- Zhou Yunlei College of Life Science, Beijing Normal University, 100875, Beijing, China aut NATIONALLICENCE 700 1- Ma Qiang College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut NATIONALLICENCE 700 1- Liu Tao College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut NATIONALLICENCE 700 1- Ai Shiyun College of Chemistry and Material Science, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut NATIONALLICENCE 700 1- Zhu Lusheng College of Resources and Environment, Shandong Agricultural University, 271018, Tai'an, Shandong, China aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 172/3-4(2011-03-01), 343-349 0026-3672 172:3-4<343 2011 172 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer