caa a22 4500 445879750 CHVBK 20180317145538.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00604-010-0482-2 doi (NATIONALLICENCE)springer-10.1007/s00604-010-0482-2 A simple poly(dimethylsiloxane) electrophoresis microchip with an integrated contactless conductivity detector [Elektronische Daten] [Benyan Liu, Qinghui Jin, Yi Zhang, Dirk Mayer, Hans-Joachim Krause, Jianlong Zhao, Andreas Offenhäusser] A simple poly(dimethylsiloxane) (PDMS) microchip was fabricated with an integrated contactless conductivity detector. This microchip consists of a PDMS cover sheet with embedded channels and a glass substrate holding the electrodes. The electrodes are insulated from the microchannel by a PDMS membrane. n-Dodecyl β-D-maltoside was utilized to modify the channel surface to improve its hydrophilicity and to reduce the strong absorption of PDMS. A readout system based on a multiplier was set up for detection, and a commonly used rectifier circuit was added to this system for direct comparison. A mixture of inorganic cations (K+, Na+, Li+) was successfully separated in 100 × 30μm microchannels and detected by applying a sinusoidal wave with a frequency of 100kHz and 6Vp-p. This microchip system was characterized in terms of sensitivity, reproducibility and linearity. It is suitable for mass production due to its robustness, high reproducibility, ease of fabrication and low cost. This work provides a valuable contribution to the realization of low-noise and high-sensitivity portable devices applicable to food and environmental detection fields. Figure Springer-Verlag, 2010 PDMS microchip nationallicence Contactless conductivity detection nationallicence Multiplier nationallicence Rectifier nationallicence Liu Benyan State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 865 Chang Ning Road, 200050, Shanghai, China aut Jin Qinghui State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 865 Chang Ning Road, 200050, Shanghai, China aut Zhang Yi Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut Mayer Dirk Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut Krause Hans-Joachim Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut Zhao Jianlong State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 865 Chang Ning Road, 200050, Shanghai, China aut Offenhäusser Andreas Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut Microchimica Acta Springer Vienna 172/1-2(2011-02-01), 193-198 0026-3672 172:1-2<193 2011 172 604 https://doi.org/10.1007/s00604-010-0482-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-010-0482-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Benyan State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 865 Chang Ning Road, 200050, Shanghai, China aut NATIONALLICENCE 700 1- Jin Qinghui State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 865 Chang Ning Road, 200050, Shanghai, China aut NATIONALLICENCE 700 1- Zhang Yi Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut NATIONALLICENCE 700 1- Mayer Dirk Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut NATIONALLICENCE 700 1- Krause Hans-Joachim Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut NATIONALLICENCE 700 1- Zhao Jianlong State Key Lab of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, 865 Chang Ning Road, 200050, Shanghai, China aut NATIONALLICENCE 700 1- Offenhäusser Andreas Institute for Bio- and Nanosystems-2, Forschungszentrum Juelich, 52425, Juelich, Germany aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 172/1-2(2011-02-01), 193-198 0026-3672 172:1-2<193 2011 172 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer