caa a22 4500 445879874 CHVBK 20180317145539.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00604-010-0464-4 doi (NATIONALLICENCE)springer-10.1007/s00604-010-0464-4 Biomimetic norfloxacin sensors made of molecularly-imprinted materials for potentiometric transduction [Elektronische Daten] [Felismina Moreira, Victor Freitas, Maria Sales] A biomimetic sensor for norfloxacin is presented that is based on host-guest interactions and potentiometric transduction. The artificial host was imprinted into polymers made from methacrylic acid and/or 2-vinyl pyridine. The resulting particles were entrapped in a plasticized poly(vinyl chloride) (PVC) matrix. The sensors exhibit near-Nernstian response in steady state evaluations, and detection limits range from 0.40 to 1.0μg mL−1, respectively, and are independent of pH values at between 2 and 6, and 8 and 11, respectively. Good selectivity was observed over several potential interferents. In flowing media, the sensors exhibit fast response, a sensitivity of 68.2mV per decade, a linear range from 79μM to 2.5mM, a detection limit of 20μg mL−1, and a stable baseline. The sensors were successfully applied to field monitoring of norfloxacin in fish samples, biological samples, and pharmaceutical products. Figure Springer-Verlag, 2010 Norfloxacin nationallicence Molecularly-imprinted sensors nationallicence Potentiometry nationallicence FIA nationallicence Fish nationallicence Moreira Felismina REQUIMTE, Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut Freitas Victor Faculdade Ciências da Universidade do Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal aut Sales Maria REQUIMTE, Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut Microchimica Acta Springer Vienna 172/1-2(2011-02-01), 15-23 0026-3672 172:1-2<15 2011 172 604 https://doi.org/10.1007/s00604-010-0464-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-010-0464-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Moreira Felismina REQUIMTE, Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut NATIONALLICENCE 700 1- Freitas Victor Faculdade Ciências da Universidade do Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal aut NATIONALLICENCE 700 1- Sales Maria REQUIMTE, Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 172/1-2(2011-02-01), 15-23 0026-3672 172:1-2<15 2011 172 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer