caa a22 4500 445880155 CHVBK 20180317145540.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00604-011-0671-7 doi (NATIONALLICENCE)springer-10.1007/s00604-011-0671-7 Disposable solid state probe for optical screening of chlorpromazine [Elektronische Daten] [Joana Guerreiro, Maria Sales] We are presenting a simple, low-cost and rapid solid-state optical probe for screening chlorpromazine (CPZ) in aquacultures. The method exploits the colourimetric reaction between CPZ and Fe(III) ion that occurs at a solid/liquid interface, the solid layer consisting of ferric iron entrapped in a layer of plasticized PVC. If solutions containing CPZ are dropped onto such a layer, a colour change occurs from light yellow to dark pink or even light blue, depending on the concentration of CPZ. Visual inspection enables the concentration of CPZ to be estimated. The resulting colouration was also monitored by digital image collection for a more accurate quantification. The three coordinates of the hue, saturation and lightness system were obtained by standard image processing along with mathematical data treatment. The parameters affecting colour were assessed and optimized. Studies were conducted by visible spectrophotometry and digital image acquisition, respectively. The response of the optimized probe towards the concentration of CPZ was tested for several mathematical transformations of the colour coordinates, and a linear relation was found for the sum of hue and luminosity. The limit of detection is 50μM (corresponding to about 16μg per mL). The probe enables quick screening for CPZ in real water samples with prior sample treatment. Figure Springer-Verlag, 2011 Chlorpromazine nationallicence Colourimetry nationallicence Optical probe nationallicence Aquaculture nationallicence Guerreiro Joana BioMark, Sensor Research/Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut Sales Maria BioMark, Sensor Research/Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut Microchimica Acta Springer Vienna 175/3-4(2011-12-01), 323-331 0026-3672 175:3-4<323 2011 175 604 https://doi.org/10.1007/s00604-011-0671-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0671-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Guerreiro Joana BioMark, Sensor Research/Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut NATIONALLICENCE 700 1- Sales Maria BioMark, Sensor Research/Instituto Superior de Engenharia do Porto, R. Dr. António Bernardino de Almeida, 431, 4200-072, Porto, Portugal aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 175/3-4(2011-12-01), 323-331 0026-3672 175:3-4<323 2011 175 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer