caa a22 4500 44588018X CHVBK 20180317145540.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00604-011-0658-4 doi (NATIONALLICENCE)springer-10.1007/s00604-011-0658-4 Electrochemical investigation of a glassy carbon electrode modified with carbon nanotubes decorated with (poly)crystalline gold [Elektronische Daten] [Antonio Radoi, Simona-Carmen Litescu, Sandra Eremia, Mihaela Miu, Mihai Danila, Adrian Dinescu, Gabriel-Lucian Radu] Multiwalled carbon nanotubes with nanosized sputtered gold were used to modify a glassy carbon electrode (GCE). The substrate was characterized by scanning electron microscopy (SEM), X-ray diffraction, cyclic voltammetry and amperometry. SEM micrographs indicated an uniform coverage of the carbon nanotubes with nanosized (poly)crystalline gold. Cyclic voltammetry reveals that peak separation of the unmodified GCE in the presence of 1mM ferricyanide is 131mV, but 60mV only for the modified GCE. In addition, the oxidation of NADH (1mmolL−1 solution) begins at negative potentials (around −100mV vs. Ag/AgCl), and the anodic peak potential (corresponding to the irreversible oxidation of NADH) is found at +94mV. The effect of pH on the electrocatalytic activity was studied in the range from 5.4 to 8.0. The relationship between the anodic peak potential and the pH indicated a variation of −33.5mV/pH which is in agreement with a two-electron and one-proton reaction mechanism. Amperometry, performed at either −50 or +50mV vs. an Ag/AgCl reference electrode, indicates that the modified electrode is a viable amperometric sensor for NADH. At a working potential of +50mV, the response to NADH is linear in the concentration range from 1 to 100μmolL−1, with an RSD of 6% (n = 4). Figure Multiwalled carbon nanotubes with nanosized sputtered gold were used to modify a glassy carbon electrode. The oxidation of NADH (1mmolL−1) begins at negative potentials (around −100mV vs. Ag/AgCl), and the anodic peak potential (corresponding to the irreversible oxidation of NADH) is found at +94mV. Springer-Verlag, 2011 Carbon nanotubes nationallicence (Poly)crystalline gold nationallicence Glassy carbon electrode nationallicence NADH nationallicence Radoi Antonio National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut Litescu Simona-Carmen Centre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, Bucharest, Romania aut Eremia Sandra Centre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, Bucharest, Romania aut Miu Mihaela National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut Danila Mihai National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut Dinescu Adrian National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut Radu Gabriel-Lucian Centre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, Bucharest, Romania aut Microchimica Acta Springer Vienna 175/1-2(2011-10-01), 97-104 0026-3672 175:1-2<97 2011 175 604 https://doi.org/10.1007/s00604-011-0658-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0658-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Radoi Antonio National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut NATIONALLICENCE 700 1- Litescu Simona-Carmen Centre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, Bucharest, Romania aut NATIONALLICENCE 700 1- Eremia Sandra Centre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, Bucharest, Romania aut NATIONALLICENCE 700 1- Miu Mihaela National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut NATIONALLICENCE 700 1- Danila Mihai National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut NATIONALLICENCE 700 1- Dinescu Adrian National Institute for Research and Development in Microtechnology (IMT-Bucharest), 126A Erou Iancu Nicolae, 077190, Bucharest, Romania aut NATIONALLICENCE 700 1- Radu Gabriel-Lucian Centre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, Bucharest, Romania aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 175/1-2(2011-10-01), 97-104 0026-3672 175:1-2<97 2011 175 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer