caa a22 4500 445880368 CHVBK 20180317145541.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00604-011-0652-x doi (NATIONALLICENCE)springer-10.1007/s00604-011-0652-x Voltammetric sensing of paracetamol, dopamine and 4-aminophenol at a glassy carbon electrode coated with gold nanoparticles and an organophillic layered double hydroxide [Elektronische Daten] [Huanshun Yin, Kun Shang, Xiaomeng Meng, Shiyun Ai] A differential pulse voltammetric method was developed for the simultaneous determination of paracetamol, 4-aminophenol and dopamine at pH 7.0 using a glassy carbon electrode (GCE) coated with gold nanoparticles (AuNPs) and a layered double hydroxide sodium modified with dodecyl sulfate (SDS-LDH). The modified electrode displays excellent redox activity towards paracetamol, and the redox current is increased (and the corresponding over-potential decreased) compared to those of the bare GCE, the AuNPs-modified GCE, and the SDS-LDH-modified GCE. The modified electrode enables the determination of paracetamol in the concentration range from 0.5 to 400μM, with a detection limit of 0.13μM (at an S/N of 3). The sensor was successfully applied to the stimultaneous determination of paracetamol and dopamine, and of paracetamol and 4-aminophenol, respectively, in pharmaceutical tablets and in spiked human serum samples. Figure 1. Gold nanoparticles and organophillic layered double hydroxide modified glassy carbon electrode was fabricated. 2. The modified electrode displayed excellent redox activity towards paracetamol. 3. This electrode was successfully applied to the simultaneous determination of paracetamol and dopamine, and of paracetamol and 4-aminophenol, respectively Springer-Verlag, 2011 Paracetamol nationallicence Layered double hydroxide nationallicence Gold nanoparticles nationallicence Anionic surfactant nationallicence Electrochemical determination nationallicence Yin Huanshun College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut Shang Kun College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut Meng Xiaomeng College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut Ai Shiyun College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut Microchimica Acta Springer Vienna 175/1-2(2011-10-01), 39-46 0026-3672 175:1-2<39 2011 175 604 https://doi.org/10.1007/s00604-011-0652-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0652-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yin Huanshun College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut NATIONALLICENCE 700 1- Shang Kun College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut NATIONALLICENCE 700 1- Meng Xiaomeng College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut NATIONALLICENCE 700 1- Ai Shiyun College of Chemistry and Material Science, Shandong Agricultural University, Taian, 271018, Shandong, China aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 175/1-2(2011-10-01), 39-46 0026-3672 175:1-2<39 2011 175 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer