caa a22 4500 445880597 CHVBK 20180317145541.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00604-011-0580-9 doi (NATIONALLICENCE)springer-10.1007/s00604-011-0580-9 Electrochemical sensor for monitoring the photodegradation of catechol based on DNA-modified graphene oxide [Elektronische Daten] [Lili Wei, Joanna Borowiec, Lihua Zhu, Jingdong Zhang] We have immobilized DNA on a glassy carbon electrode (GCE) modified with graphene oxide (GO) to develop an electrochemical biosensor for catechol. Compared to carbon nanotubes, the use of GO dramatically improved the electrooxidative current of the guanine and adenine moieties in DNA but retained the low background current of unmodified GCEs. Factors such as DNA adsorption time, DNA concentration and pH of solution were investigated to optimize experimental conditions. In the presence of catechol, the voltammetric response to DNA was inhibited due to the interaction between DNA and catechol. The response to adenine is linearly proportional to the concentration of catechol in the range from 1.0 × 10−6 to 1.0 × 10−4mol·L−1. If catechol is degraded by the combined action of UV light and hydrogen peroxide, the response to DNA is restored. Thus, the modified electrode can act as an efficient biosensor for monitoring the degradation of catechol. Figure GO dramatically improved the electrooxidative current of the guanine and adenine moieties in DNA but retained the low background current of unmodified GCEs. While the DNA/GO-modified electrode was applied to monitor catechol, it showed sensitive response to catechol before and after photodegradation treatment. Springer-Verlag, 2011 Graphene oxide-modified electrode nationallicence DNA sensor nationallicence Catechol nationallicence Photodegradation nationallicence Direct electrochemistry of DNA nationallicence Wei Lili College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut Borowiec Joanna College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut Zhu Lihua College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut Zhang Jingdong College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut Microchimica Acta Springer Vienna 173/3-4(2011-06-01), 439-443 0026-3672 173:3-4<439 2011 173 604 https://doi.org/10.1007/s00604-011-0580-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0580-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wei Lili College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut NATIONALLICENCE 700 1- Borowiec Joanna College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut NATIONALLICENCE 700 1- Zhu Lihua College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Jingdong College of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, 430074, Wuhan, People's Republic of China aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 173/3-4(2011-06-01), 439-443 0026-3672 173:3-4<439 2011 173 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer