caa a22 4500 445881062 CHVBK 20180317145543.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00604-011-0556-9 doi (NATIONALLICENCE)springer-10.1007/s00604-011-0556-9 Electrochemistry and voltammetric determination of L-tryptophan and L-tyrosine using a glassy carbon electrode modified with a Nafion/TiO2-graphene composite film [Elektronische Daten] [Yang Fan, Jin-Hang Liu, Hai-Ting Lu, Qin Zhang] We describe a glassy carbon electrode (GCE) modified with a film composed of Nafion and TiO2-graphene (TiO2-GR) nanocomposite, and its voltammetric response to the amino acids L-tryptophane (Trp) and L-tyrosine (Tyr). The incorporation of TiO2 nanoparticles with graphene significantly improves the electrocatalytic activity and voltammetric response compared to electrodes modified with Nafion/graphene only. The Nafion/TiO2-GR modified electrode was used to determine Trp and Tyr with detection limits of 0.7 and 2.3μM, and a sensitivity of 75.9 and 22.8μA mM−1 for Trp and Tyr, respectively. Figure The electrochemical sensor based on Nafion/TiO2-GR composite film modified GCE was presented. The integration of TiO2 nanoparticles with graphene provides an efficient microenvironment to promote the electrochemical reaction of amino acids Trp and Tyr. The fabricated electrochemical sensor exhibits favorable analytical performance for Trp and Tyr, with high sensitivity, low detection limit and good reproducibility. Springer-Verlag, 2011 Graphene nationallicence TiO2-graphene nanocomposite nationallicence Electrochemical sensor nationallicence Tryptophan nationallicence Tyrosine nationallicence Fan Yang College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut Liu Jin-Hang College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut Lu Hai-Ting College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut Zhang Qin College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut Microchimica Acta Springer Vienna 173/1-2(2011-04-01), 241-247 0026-3672 173:1-2<241 2011 173 604 https://doi.org/10.1007/s00604-011-0556-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0556-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fan Yang College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut NATIONALLICENCE 700 1- Liu Jin-Hang College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut NATIONALLICENCE 700 1- Lu Hai-Ting College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Qin College of Chemistry and Chemical Engineering, Xinyang Normal University, 464000, Xinyang, People's Republic of China aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 173/1-2(2011-04-01), 241-247 0026-3672 173:1-2<241 2011 173 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer