caa a22 4500 445881224 CHVBK 20180317145544.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00604-011-0615-2 doi (NATIONALLICENCE)springer-10.1007/s00604-011-0615-2 Centri-voltammetry for biosensing systems: biocentri-voltammetric xanthine detection [Elektronische Daten] [Ulku Anik, Serdar Çevik] Centri-voltammetry is a method that combines centrifugation and voltammetry. This method, developed by our group in 2003, yielded promising results when applied to trace analysis of metal ios. We demonstrate here the first application of centri-voltammetry to biosensing systems. A xanthine biosensor was constructed by immobilizing xanthine oxidase on a planar platinum electrode which then was placed at the bottom of a centri-voltammetric cell. The experimental parameters were optimized to give two linear ranges. The first is from 0.1 to 1μM, and the second from 5 to 50μM. The RSD is 3.4 (n = 5). The biosensor was applied to the determination of xanthine in wine and in urine. Calculated recoveries are 101 ± 0.61% (n = 3) for wine samples, and 102 ± 0.556% (n = 3) for urine samples. Figure Centri-voltammetry is a method, which combines the advantages of centrifugation and voltammetry. In this work, the performance of biocentri-voltammetry for xanthine detection has been investigated. After the optimization studies and examination of analytical characteristics, developed centri-voltammetric biosensor was applied for xanthine detection in wine and in urine samples. Springer-Verlag, 2011 Centri-voltammetry nationallicence Xanthine nationallicence Biosensors nationallicence Centrifuge nationallicence Anik Ulku Faculty of Science, Chemistry Department, Mugla University, 48000, Kötekli Mugla, Turkiye aut Çevik Serdar Faculty of Science, Chemistry Department, Mugla University, 48000, Kötekli Mugla, Turkiye aut Microchimica Acta Springer Vienna 174/3-4(2011-09-01), 207-212 0026-3672 174:3-4<207 2011 174 604 https://doi.org/10.1007/s00604-011-0615-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0615-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Anik Ulku Faculty of Science, Chemistry Department, Mugla University, 48000, Kötekli Mugla, Turkiye aut NATIONALLICENCE 700 1- Çevik Serdar Faculty of Science, Chemistry Department, Mugla University, 48000, Kötekli Mugla, Turkiye aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 174/3-4(2011-09-01), 207-212 0026-3672 174:3-4<207 2011 174 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer