caa a22 4500 445881488 CHVBK 20180317145544.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s00604-011-0595-2 doi (NATIONALLICENCE)springer-10.1007/s00604-011-0595-2 Evaluation of the binding specificity of electrosynthesized poly- ortho -phenylenediamine molecularly imprinted with metal chelates [Elektronische Daten] [Feng Lu, Lianyan Wang, Fuquan Wu, Xiaofang Ying, Ren'ao Gu, Jianlin Yao, Hailu Zhang, Zongwu Deng] We have examined the specificity of electrosynthesized poly-o-phenylenediamine as a kind of material molecularly imprinted with metal chelates. Molecularly imprinted polymers (MIPs) were prepared in situ by an electrochemical method. The EDTA chelate complexes of Cu(II), Zn(II), Fe(III) and Cd(II) ions were used as templates of the MIPs deposited on a gold electrode of a quartz crystal microbalance (QCM). The binding ability and specificity of the MIPs were investigated via the frequency response of the QCM to the adsorption of the template chelates and their analogs. Linear relationships are observed between the frequency shift and the concentration of the template chelates over a typical range of ~10−6 to ~10−4mol·L−1. The results reveal good binding specificity of such MIPs for their templates over structurally related analogs, but the selectivity coefficients are less significant than that for enantiomers. The results also suggest no significant correlation between binding specificity and the ionic (or atomic) radius of the investigated metal ions. The observed specificity is qualitatively attributed to the overall conformational difference of the metal-EDTA complexes resulting from their difference in both ionic radius and electronic structures. Figure Schematic Representation of the Molecular Imprinting Procedures. The metal ions chelate with EDTA to form metal-EDTA chelates as the template, then polymerization is initiated by an electrochemical method. After the polymerization, the templates are removed to create cavities in the polymer film which have binding ability and specificity to the templates. Springer-Verlag, 2011 Molecularly imprinted polymers nationallicence Binding specificity nationallicence Electrochemical method nationallicence Metal chelate nationallicence Lu Feng College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Suzhou, People's Republic of China aut Wang Lianyan Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut Wu Fuquan Suzhou Environmental Monitor Centre, 215004, Suzhou, People's Republic of China aut Ying Xiaofang Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut Gu Ren'ao College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Suzhou, People's Republic of China aut Yao Jianlin College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Suzhou, People's Republic of China aut Zhang Hailu Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut Deng Zongwu Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut Microchimica Acta Springer Vienna 174/1-2(2011-07-01), 47-54 0026-3672 174:1-2<47 2011 174 604 https://doi.org/10.1007/s00604-011-0595-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00604-011-0595-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lu Feng College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Wang Lianyan Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Wu Fuquan Suzhou Environmental Monitor Centre, 215004, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Ying Xiaofang Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Gu Ren'ao College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Yao Jianlin College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Hailu Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 700 1- Deng Zongwu Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 215123, Suzhou, People's Republic of China aut NATIONALLICENCE 773 0- Microchimica Acta Springer Vienna 174/1-2(2011-07-01), 47-54 0026-3672 174:1-2<47 2011 174 604 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer