caa a22 4500 445882379 CHVBK 20180317145547.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10157-010-0369-x doi (NATIONALLICENCE)springer-10.1007/s10157-010-0369-x Methicillin-resistant Staphylococcus-aureus -associated glomerulonephritis on the decline: decreased incidence since the 1990s [Elektronische Daten] [Joichi Usui, Masaki Kobayashi, Itaru Ebihara, Akio Koyama, Kunihiro Yamagata] We believe that bacterial-infection-associated glomerulonephritis (GN), so-called methicillin-resistant Staphylococcus aureus (MRSA)-GN, was exterminated in Japan. The control of bacterial infection is the most important part of infection-associated GN. In 1990s Japan, hospital-associated MRSA (HA-MRSA) caused MRSA-GN outbreaks. On the other hand, MRSA-GN incidence has been quite limited since 2000. This epidemiological transition suggests that antibacterial therapies and health programs for HA-MRSA infection in Japan were effective against MRSA-GN. Moreover, it appears that staphylococcal superantigens act in the pathogenesis of GN. The change of superantigen production might have influenced to the disappearance of MRSA-GN. If HA-MRSA-producing superantigen outbreaks occur in developing countries, our experience in Japan can provide guiding principles for preventing and eradicating GN. Japanese Society of Nephrology, 2010 Hospital-acquired MRSA nationallicence Superantigen nationallicence Rapidly progressive glomerulonephritis nationallicence Usui Joichi Department of Nephrology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan aut Kobayashi Masaki Department of Nephrology, Tokyo Medical University, Ibaraki Medical Center, Ami, Ibaraki, Japan aut Ebihara Itaru Department of Nephrology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan aut Koyama Akio Ibaraki Prefectural University, Ami, Ibaraki, Japan aut Yamagata Kunihiro Department of Nephrology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan aut Clinical and Experimental Nephrology Springer Japan 15/1(2011-02-01), 184-186 1342-1751 15:1<184 2011 15 10157 https://doi.org/10.1007/s10157-010-0369-x text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-010-0369-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Usui Joichi Department of Nephrology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Kobayashi Masaki Department of Nephrology, Tokyo Medical University, Ibaraki Medical Center, Ami, Ibaraki, Japan aut NATIONALLICENCE 700 1- Ebihara Itaru Department of Nephrology, Mito Saiseikai General Hospital, Mito, Ibaraki, Japan aut NATIONALLICENCE 700 1- Koyama Akio Ibaraki Prefectural University, Ami, Ibaraki, Japan aut NATIONALLICENCE 700 1- Yamagata Kunihiro Department of Nephrology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/1(2011-02-01), 184-186 1342-1751 15:1<184 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer