caa a22 4500 445882409 CHVBK 20180317145547.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10157-010-0362-4 doi (NATIONALLICENCE)springer-10.1007/s10157-010-0362-4 Tumoral calcinosis associated with hypercalcemia in a patient with chronic renal failure [Elektronische Daten] [Ryoko Horikoshi, Tetsu Akimoto, Daishi Meguro, Osamu Saito, Yasuhiro Ando, Shigeaki Muto, Eiji Kusano] A 56-year-old male with chronic renal failure was admitted to the hospital because of progressive hip pain, appetite loss, general fatigue, and hypercalcemia. Slight pain had developed in the left hip 3months before the initiation of hemodialysis, which subsequently developed into hyperalgesia. The patient was suspected to have sarcoidosis based on the elevated serum angiotensin-converting enzyme and lysozyme levels, and the ocular finding characterized by punched out chorioretinal scarring, although this could not be confirmed by histological evaluations. There was an abnormal uptake of gallium in the dependent portion of the tumoral calcinosis, which could have suggested either the presence of granulomatous sarcoid tissue within the calcified mass or active calcification associated with an inflammatory reaction. Elevated serum concentrations of 1,25-dihydroxyvitamin D3, which should be implicated in the development of hypercalcemia, promptly decreased after the administration of steroids. Steroid administration subsequently led to a decrease in the serum calcium and relief of the hip pain. This was a rare case of sarcoidosis associated with symptomatic tumoral calcinosis and hypercalcemia. The diagnostic significance of a gallium scan in this case will also be discussed. Japanese Society of Nephrology, 2010 Tumoral calcinosis nationallicence Hypercalcemia nationallicence Sarcoidosis nationallicence Gallium scintigraphy nationallicence Zoledronate nationallicence Horikoshi Ryoko Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Akimoto Tetsu Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Meguro Daishi Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Saito Osamu Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Ando Yasuhiro Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Muto Shigeaki Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Kusano Eiji Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut Clinical and Experimental Nephrology Springer Japan 15/1(2011-02-01), 154-158 1342-1751 15:1<154 2011 15 10157 https://doi.org/10.1007/s10157-010-0362-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-010-0362-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Horikoshi Ryoko Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 700 1- Akimoto Tetsu Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 700 1- Meguro Daishi Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 700 1- Saito Osamu Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 700 1- Ando Yasuhiro Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 700 1- Muto Shigeaki Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 700 1- Kusano Eiji Division of Nephrology, Department of Internal Medicine, Jichi Medical University, 3311-1 Yakushiji, 329-0498, Shimotsuke, Tochigi, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/1(2011-02-01), 154-158 1342-1751 15:1<154 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer