caa a22 4500 445882735 CHVBK 20180317145549.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10157-011-0509-y doi (NATIONALLICENCE)springer-10.1007/s10157-011-0509-y Significance of past history of renal failure for the detection of high-risk individuals for cardiovascular and end-stage renal disease: analysis of data from a nationwide health checkup [Elektronische Daten] [Kazunobu Ichikawa, Tsuneo Konta, Ami Ikeda, Shouichi Fujimoto, Kunitoshi Iseki, Toshiki Moriyama, Kunihiro Yamagata, Kazuhiko Tsuruya, Hideaki Yoshida, Koichi Asahi, Issei Kurahashi, Yasuo Ohashi, Tsuyoshi Watanabe] Background: Clinical information regarding risk factors may be helpful in the detection of various diseases. This cross-sectional study examined the characteristics of subjects with past history of renal failure, and assessed whether this information would be useful for the efficient detection of high-risk individuals for chronic kidney disease (CKD) and cardiovascular disease (CVD) at health checkup. Methods: This study utilized data from a nationwide health checkup, "The Specific Health Check and Guidance in Japan,” and data for 250,130 adult subjects were analyzed. Subjects with self-reported history of renal failure and receiving dialysis therapy were defined as having a history of renal failure. Results: Among total participants, there were 1,400 (0.6%) with a history of renal failure. The prevalence of a history of renal failure was higher in subjects with CKD than in those without CKD (1.5 vs. 0.3%, P<0.001) and increased with progression of the stage of CKD (0.9-43.5%). Subjects with a history of renal failure had a reduced estimated glomerular filtration rate (44.6±20.3ml/min/1.73m2) and a higher prevalence of CKD (50.5%) and CVD (31.9%), compared with subjects with hypertension, diabetes or metabolic syndrome. Multivariate logistic regression analysis showed an independent association between a history of CVD and renal failure (odds ratio 3.68, 95% confidence interval 3.26-4.15), after adjustment for confounding factors. Conclusions: A history of renal failure was strongly associated with advanced CKD and CVD. Information regarding history of renal failure could be utilized to efficiently detect high-risk individuals at health checkup. Japanese Society of Nephrology, 2011 Chronic kidney disease nationallicence Epidemiology nationallicence Past history nationallicence Ichikawa Kazunobu Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, 990-9585, Yamagata, Japan aut Konta Tsuneo Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, 990-9585, Yamagata, Japan aut Ikeda Ami Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, 990-9585, Yamagata, Japan aut Fujimoto Shouichi Dialysis Division, University of Miyazaki Hospital, Miyazaki, Japan aut Iseki Kunitoshi Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Moriyama Toshiki Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Yamagata Kunihiro Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Tsuruya Kazuhiko Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Yoshida Hideaki Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Asahi Koichi Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Kurahashi Issei Department of Biostatistics/Epidemiology and Preventive Health Sciences, School of Health Sciences and Nursing, University of Tokyo, Tokyo, Japan aut Ohashi Yasuo Department of Biostatistics/Epidemiology and Preventive Health Sciences, School of Health Sciences and Nursing, University of Tokyo, Tokyo, Japan aut Watanabe Tsuyoshi Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut Clinical and Experimental Nephrology Springer Japan 15/6(2011-12-01), 841-847 1342-1751 15:6<841 2011 15 10157 https://doi.org/10.1007/s10157-011-0509-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-011-0509-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ichikawa Kazunobu Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, 990-9585, Yamagata, Japan aut NATIONALLICENCE 700 1- Konta Tsuneo Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, 990-9585, Yamagata, Japan aut NATIONALLICENCE 700 1- Ikeda Ami Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, 990-9585, Yamagata, Japan aut NATIONALLICENCE 700 1- Fujimoto Shouichi Dialysis Division, University of Miyazaki Hospital, Miyazaki, Japan aut NATIONALLICENCE 700 1- Iseki Kunitoshi Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 700 1- Moriyama Toshiki Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 700 1- Yamagata Kunihiro Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 700 1- Tsuruya Kazuhiko Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 700 1- Yoshida Hideaki Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 700 1- Asahi Koichi Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 700 1- Kurahashi Issei Department of Biostatistics/Epidemiology and Preventive Health Sciences, School of Health Sciences and Nursing, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Ohashi Yasuo Department of Biostatistics/Epidemiology and Preventive Health Sciences, School of Health Sciences and Nursing, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Watanabe Tsuyoshi Steering Committee for the "Research on the Positioning of Chronic Kidney Disease (CKD) in Specific Health Check and Guidance in Japan”, Otawara, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/6(2011-12-01), 841-847 1342-1751 15:6<841 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer