caa a22 4500 445883111 CHVBK 20180317145550.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10157-011-0427-z doi (NATIONALLICENCE)springer-10.1007/s10157-011-0427-z Use of small doses of furosemide in chronic kidney disease patients with residual renal function undergoing hemodialysis [Elektronische Daten] [Helton Lemes, Salustiano Araujo, Daniella Nascimento, Danny Cunha, Cesar Garcia, Vinicius Queiroz, Sebastião Ferreira-Filho] Background: The objective of the present study was to verify whether chronic renal patients on hemodialysis (HD) with residual diuresis who were using small doses of furosemide present different levels of urinary volume and sodium excretion compared to patients with residual diuresis who do not use this drug. Methods: We studied 19 chronic renal patients on HD who presented any level of residual diuresis. Urine was collected during the 24-h interdialytic period, and physical examinations and blood sampling took place immediately before the start of HD. Patients were divided into two groups: the diuretic group (DG, n=10), in which patients had been using 40mg of furosemide for at least 3months, and the non-diuretic group (NDG, n=9), in which patients used no diuretics. Results: Although both groups presented the same average glomerular filtration rate (p>0.05) and time in dialysis (p>0.05) the DG presented an average of twice the urinary volume in 24h (1142±184 vs. 453±135ml/24h, respectively; p=0.008) and double the total excreted sodium mass compared to patients in the NDG (112±22.4 vs. 45.2±16.0mEq/24h, respectively; p=0.02). Conclusion: The results of this study have shown that chronic use of small doses of furosemide in chronic renal patients with residual diuresis could increase urinary volume and sodium excretion compared to patients who did not use this drug. Japanese Society of Nephrology, 2011 Furosemide nationallicence Chronic renal failure nationallicence Residual renal function nationallicence Lemes Helton Nefroclínica de Uberlândia, Rua Paraíba 3055, 38400-000, Uberlândia, MG, Brazil aut Araujo Salustiano Universidade Federal de Uberlândia, Uberlândia, Brazil aut Nascimento Daniella Universidade Federal de Uberlândia, Uberlândia, Brazil aut Cunha Danny Universidade Federal de Uberlândia, Uberlândia, Brazil aut Garcia Cesar Universidade Federal de Uberlândia, Uberlândia, Brazil aut Queiroz Vinicius Universidade Federal de Uberlândia, Uberlândia, Brazil aut Ferreira-Filho Sebastião Nefroclínica de Uberlândia, Rua Paraíba 3055, 38400-000, Uberlândia, MG, Brazil aut Clinical and Experimental Nephrology Springer Japan 15/4(2011-08-01), 554-559 1342-1751 15:4<554 2011 15 10157 https://doi.org/10.1007/s10157-011-0427-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-011-0427-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lemes Helton Nefroclínica de Uberlândia, Rua Paraíba 3055, 38400-000, Uberlândia, MG, Brazil aut NATIONALLICENCE 700 1- Araujo Salustiano Universidade Federal de Uberlândia, Uberlândia, Brazil aut NATIONALLICENCE 700 1- Nascimento Daniella Universidade Federal de Uberlândia, Uberlândia, Brazil aut NATIONALLICENCE 700 1- Cunha Danny Universidade Federal de Uberlândia, Uberlândia, Brazil aut NATIONALLICENCE 700 1- Garcia Cesar Universidade Federal de Uberlândia, Uberlândia, Brazil aut NATIONALLICENCE 700 1- Queiroz Vinicius Universidade Federal de Uberlândia, Uberlândia, Brazil aut NATIONALLICENCE 700 1- Ferreira-Filho Sebastião Nefroclínica de Uberlândia, Rua Paraíba 3055, 38400-000, Uberlândia, MG, Brazil aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/4(2011-08-01), 554-559 1342-1751 15:4<554 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer