caa a22 4500 445883154 CHVBK 20180317145550.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10157-011-0443-z doi (NATIONALLICENCE)springer-10.1007/s10157-011-0443-z Obesity and chronic kidney disease in patients with chronic heart failure: an insight from the China Heart Survey [Elektronische Daten] [Hao Liu, Hong Shi, Jinming Yu, Fang Chen, Qingwu Jiang, Dayi Hu] Background: Obesity and decreased kidney function have been shown to be prevalent in Western patients with heart failure; however, whether this phenomenon exists in Chinese patients with chronic heart failure (CHF) is not known. Methods and results: One thousand and nine patients with CHF from the China Heart Survey were assessed. The prevalence of chronic kidney disease (CKD) was 34.2%, and there was a stepwise increase in the prevalence of CKD with New York Heart Association (NYHA) classes (P<0.001). Moreover, patients with CKD had a significantly elevated risk for developing severe extent of CHF (OR=1.69, 95% CI: 1.27-2.24, P<0.001). The prevalence of obesity and central obesity was 35.7% and 62.5%, respectively. Notably, there was a downward trend in the prevalence of obesity with advanced NYHA classes (trend test, P=0.003). Multivariate analysis further supported the finding that obesity, but not central obesity, was inversely associated with the extent of CHF (OR=0.72, 95% CI: 0.55-0.94, P=0.017). Conclusions: Renal dysfunction is common in Chinese patients with CHF and is independently associated with advanced NYHA classes. Obesity was inversely associated with the extent of CHF, which further supports the notion that obesity confers improved prognosis in patients with heart failure. Japanese Society of Nephrology, 2011 Heart failure nationallicence Obesity nationallicence Central obesity nationallicence Chronic kidney disease nationallicence Liu Hao Clinical Research Institute, School of Public Health, Fudan University, 130 Dong-An Rd., 200032, Shanghai, China aut Shi Hong Tangdu Hospital, The Fourth Military Medical University, 710038, Xi'an, China aut Yu Jinming Clinical Research Institute, School of Public Health, Fudan University, 130 Dong-An Rd., 200032, Shanghai, China aut Chen Fang Department of Preventive Medicine, Tongji University School of Medicine, 200092, Shanghai, China aut Jiang Qingwu Clinical Research Institute, School of Public Health, Fudan University, 130 Dong-An Rd., 200032, Shanghai, China aut Hu Dayi Department of Cardiology, People's Hospital, Peking University, 100044, Beijing, China aut Clinical and Experimental Nephrology Springer Japan 15/4(2011-08-01), 522-528 1342-1751 15:4<522 2011 15 10157 https://doi.org/10.1007/s10157-011-0443-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-011-0443-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Hao Clinical Research Institute, School of Public Health, Fudan University, 130 Dong-An Rd., 200032, Shanghai, China aut NATIONALLICENCE 700 1- Shi Hong Tangdu Hospital, The Fourth Military Medical University, 710038, Xi'an, China aut NATIONALLICENCE 700 1- Yu Jinming Clinical Research Institute, School of Public Health, Fudan University, 130 Dong-An Rd., 200032, Shanghai, China aut NATIONALLICENCE 700 1- Chen Fang Department of Preventive Medicine, Tongji University School of Medicine, 200092, Shanghai, China aut NATIONALLICENCE 700 1- Jiang Qingwu Clinical Research Institute, School of Public Health, Fudan University, 130 Dong-An Rd., 200032, Shanghai, China aut NATIONALLICENCE 700 1- Hu Dayi Department of Cardiology, People's Hospital, Peking University, 100044, Beijing, China aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/4(2011-08-01), 522-528 1342-1751 15:4<522 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer