caa a22 4500 445883537 CHVBK 20180317145552.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10157-011-0466-5 doi (NATIONALLICENCE)springer-10.1007/s10157-011-0466-5 Geographic differences in the increasing ESRD rate have disappeared in Japan [Elektronische Daten] [Tamaki Wakamatsu-Yamanaka, Michio Fukuda, Ryo Sato, Takehiro Naito, Hiroyuki Togawa, Tatsuya Tomonari, Yoko Kato, Toshiyuki Miura, Masashi Mizuno, Tadashi Ichikawa, Sota Miyagi, Yuichi Shirasawa, Akinori Ito, Atsuhiro Yoshida, Genjiro Kimura] Background: We previously showed that there are marked geographic differences in the incidence of end-stage renal disease (ESRD) within Japan. In addition, the use of renin-angiotensin system inhibitors was found to be inversely correlated with the increasing ESRD rate. It was recently demonstrated that the incidence of ESRD due to diabetic nephropathy is declining in both Europe and USA. Therefore, we investigated the increasing ESRD rate and its geographic difference in Japan. Methods: Each year, the Japanese Society for Dialysis Therapy reports the numbers of patients initiating maintenance dialysis therapy in each prefecture of Japan. We used old (1984-1991) and recent (2001-2008) data to compare the increasing ESRD rate, which was estimated from the slope of the regression line of the annual incidence corrected for population, between the two periods in 11 regions of Japan. Results: Increasing ESRD rate almost halved, from 11.1±5.6 to 5.4±0.7/million per year from the old to the recent period. Deceleration of the increasing ESRD rate from the old to the recent period was correlated with the incidence in the old period across 11 regions (r=0.81, p<0.003); i.e., the deceleration was greater in the regions where ESRD incidence had been higher. Whereas the increasing ESRD rate was significantly different among regions in the old period, this was not the case in the recent period, resulting in uniformity throughout Japan. Conclusions: The increasing ESRD rate is slowing in Japan, and its geographic differences, previously observed, have disappeared. Japanese Society of Nephrology, 2011 End-stage renal disease nationallicence Geographic difference nationallicence Incidence nationallicence Prevention nationallicence Progression nationallicence Wakamatsu-Yamanaka Tamaki Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Fukuda Michio Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Sato Ryo Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Naito Takehiro Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Togawa Hiroyuki Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Tomonari Tatsuya Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Kato Yoko Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Miura Toshiyuki Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Mizuno Masashi Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Ichikawa Tadashi Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Miyagi Sota Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Shirasawa Yuichi Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Ito Akinori Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Yoshida Atsuhiro Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Kimura Genjiro Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut Clinical and Experimental Nephrology Springer Japan 15/5(2011-10-01), 708-713 1342-1751 15:5<708 2011 15 10157 https://doi.org/10.1007/s10157-011-0466-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-011-0466-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wakamatsu-Yamanaka Tamaki Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Fukuda Michio Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Sato Ryo Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Naito Takehiro Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Togawa Hiroyuki Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Tomonari Tatsuya Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Kato Yoko Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Miura Toshiyuki Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Mizuno Masashi Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Ichikawa Tadashi Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Miyagi Sota Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Shirasawa Yuichi Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Ito Akinori Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Yoshida Atsuhiro Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 700 1- Kimura Genjiro Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, 467-8601, Nagoya, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/5(2011-10-01), 708-713 1342-1751 15:5<708 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer