caa a22 4500 445883618 CHVBK 20180317145552.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10157-011-0469-2 doi (NATIONALLICENCE)springer-10.1007/s10157-011-0469-2 Two cases of acute renal hemorrhage undergoing maintenance hemodialysis after concurrent administration of cinacalcet [Elektronische Daten] [Kentaro Wada, Yuko Wada, Yasuhiko Iino] We report here a rare complication of renal hemorrhage in 2 male patients under treatment with long-term hemodialysis subsequent to the administration of the calcimemetic agent, cinacalcet hydrochloride. The patients presented with flank pain, peripheral hypereosinophilia and severe anemia. Computed tomography revealed a massive subcapsular hematoma on the kidney. Extensive coagulation analyses were within normal ranges. They had not been administered new medication for their complications during the 6months prior to admission, except for cinacalcet (Case 1, 14days; Case 2, 13days). A drug lymphocyte stimulating test for cinacalcet was positive in both cases. Eight percent of the patients in our hospital who were administered cinacalcet presented with complication of renal hemorrhage. Based on these findings, the final diagnosis was renal hemorrhage due to cinacalcet. They were treated conservatively because both the size of the hematoma and anemia improved. To the best of our knowledge, this is the first report concerning renal hemorrhage. Japanese Society of Nephrology, 2011 Renal hemorrhage nationallicence Hemodialysis nationallicence Cinacalcet nationallicence Wada Kentaro Division of Nephrology and Dialysis, Department of Internal Medicine, Nippon Kokan Fukuyama Hospital, 1844 Tsunoshita, Daimon-cho, 721-0927, Fukuyama, Hiroshima, Japan aut Wada Yuko Department of Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, 162-8666, Tokyo, Japan aut Iino Yasuhiko The 2nd Department of Internal Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8602, Tokyo, Japan aut Clinical and Experimental Nephrology Springer Japan 15/5(2011-10-01), 783-787 1342-1751 15:5<783 2011 15 10157 https://doi.org/10.1007/s10157-011-0469-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-011-0469-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wada Kentaro Division of Nephrology and Dialysis, Department of Internal Medicine, Nippon Kokan Fukuyama Hospital, 1844 Tsunoshita, Daimon-cho, 721-0927, Fukuyama, Hiroshima, Japan aut NATIONALLICENCE 700 1- Wada Yuko Department of Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, 162-8666, Tokyo, Japan aut NATIONALLICENCE 700 1- Iino Yasuhiko The 2nd Department of Internal Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, 113-8602, Tokyo, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/5(2011-10-01), 783-787 1342-1751 15:5<783 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer