caa a22 4500 445883774 CHVBK 20180317145553.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10157-010-0396-7 doi (NATIONALLICENCE)springer-10.1007/s10157-010-0396-7 Management of anemia in chronic kidney disease patients: baseline findings from Chronic Kidney Disease Japan Cohort Study [Elektronische Daten] [Tadao Akizawa, Hirofumi Makino, Seiichi Matsuo, Tsuyoshi Watanabe, Enyu Imai, Kosaku Nitta, Yasuo Ohashi, Akira Hishida] Background: Anemia is a factor that affects the outcome of patients with chronic kidney disease (CKD); however, there are only a few reports on the management of anemia in Japanese patients with CKD who are not on dialysis. Methods: We investigated the prevalence, related factors and management of anemia in CKD stage 3-5 patients in Japan based on the baseline data obtained from a prospective cohort study (Chronic Kidney Disease Japan Cohort). Anemia was defined as having a hemoglobin (Hb) level of <11g/dL or receiving erythropoiesis stimulating agent (ESA) therapy. Results: The result indicated that 946 out of 2,930 patients had anemia. Of these 946 patients, 385 were receiving ESA treatment for anemia and had an Hb level of 10.28±1.19g/dL (mean±SD). The percentage of these patients with an Hb level above the target of 11g/dL proposed for treatment by the Japanese guidelines, and above the maintenance level of 10g/dL approved for ESA therapy in Japan, was only 30.1 and 61.6%, respectively. In contrast, the percentage of patients receiving no ESA therapy was 67.6 and 55.7%, respectively, among those with an Hb level of <11 and <10g/dL. Conclusions: These data suggested that prevalence of anemia was high in Japanese patients with CKD stage 3-5, that the percentage of patients receiving ESA was low among those who required ESA, and that a large number of patients receiving ESA failed to maintain the recommended level of Hb. Japanese Society of Nephrology, 2011 CKD nationallicence Erythropoiesis stimulating agent (ESA) nationallicence Hemoglobin (Hb) nationallicence Anemia nationallicence Akizawa Tadao Division of Nephrology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, 142-8666, Tokyo, Japan aut Makino Hirofumi Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan aut Matsuo Seiichi Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan aut Watanabe Tsuyoshi The Third Department of Internal Medicine, Fukushima Medical College, Fukushima, Japan aut Imai Enyu Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan aut Nitta Kosaku Department of Medicine, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan aut Ohashi Yasuo Department of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, Japan aut Hishida Akira First Department of Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan aut Clinical and Experimental Nephrology Springer Japan 15/2(2011-04-01), 248-257 1342-1751 15:2<248 2011 15 10157 https://doi.org/10.1007/s10157-010-0396-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-010-0396-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akizawa Tadao Division of Nephrology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, 142-8666, Tokyo, Japan aut NATIONALLICENCE 700 1- Makino Hirofumi Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan aut NATIONALLICENCE 700 1- Matsuo Seiichi Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan aut NATIONALLICENCE 700 1- Watanabe Tsuyoshi The Third Department of Internal Medicine, Fukushima Medical College, Fukushima, Japan aut NATIONALLICENCE 700 1- Imai Enyu Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan aut NATIONALLICENCE 700 1- Nitta Kosaku Department of Medicine, Kidney Center, Tokyo Women's Medical University, Tokyo, Japan aut NATIONALLICENCE 700 1- Ohashi Yasuo Department of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Hishida Akira First Department of Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/2(2011-04-01), 248-257 1342-1751 15:2<248 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer