caa a22 4500 445883855 CHVBK 20180317145553.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10157-010-0383-z doi (NATIONALLICENCE)springer-10.1007/s10157-010-0383-z Natural history of renal cell carcinoma: a case with 18years follow-up [Elektronische Daten] [Fumitake Kai, Tatsuya Takayama, Toshiki Ito, Shinsuke Hadano, Seiichiro Ozono] A 53-year-old woman presented to our hospital with a non-metastatic 4cm renal mass in the right kidney. The patient rejected treatment, but consented to follow-up observation of her condition. The patient underwent a series of computed tomography scans to monitor the progression of the disease. We were able to observe not only an increase in renal mass size, but also involvement of para-aortic lymph nodes, inferior vena cava, and metastasis to the lung. Eighteen years after diagnosis, the subject was hospitalized and died as a result of complications of the disease. Autopsy showed the pathologic diagnosis of the renal mass to be a grade 2 clear cell carcinoma. The literature contains several papers that describe the natural history of renal masses and carcinomas over short periods; however, prior to our case, no reports existed that detailed long-term progression of renal cell carcinoma (RCC) from initial diagnosis to death. It is necessary to clarify the course that RCC takes due to its unpredictable, indolent nature. This will provide clinicians with better insight into how to manage the disease, decide on treatment options, and improve overall survival. Japanese Society of Nephrology, 2010 Renal cell carcinoma nationallicence Natural history nationallicence Active surveillance nationallicence Long-term follow-up nationallicence Kai Fumitake Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut Takayama Tatsuya Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut Ito Toshiki Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut Hadano Shinsuke Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut Ozono Seiichiro Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut Clinical and Experimental Nephrology Springer Japan 15/2(2011-04-01), 312-315 1342-1751 15:2<312 2011 15 10157 https://doi.org/10.1007/s10157-010-0383-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-010-0383-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kai Fumitake Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut NATIONALLICENCE 700 1- Takayama Tatsuya Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut NATIONALLICENCE 700 1- Ito Toshiki Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut NATIONALLICENCE 700 1- Hadano Shinsuke Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut NATIONALLICENCE 700 1- Ozono Seiichiro Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Higashi-ku, Handayama, 431-3192, Hamamatsu, Shizuoka, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/2(2011-04-01), 312-315 1342-1751 15:2<312 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer