caa a22 4500 445883898 CHVBK 20180317145553.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10157-010-0394-9 doi (NATIONALLICENCE)springer-10.1007/s10157-010-0394-9 Diffuse alveolar hemorrhage in lupus nephritis complicated by microscopic polyangiitis [Elektronische Daten] [Motohide Isono, Hisazumi Araki, Takao Haitani, Yoshikata Morita, Mako Yasuda, Noriko Kato, Koji Urasaki, Yoshinori Tsujimura] Diffuse alveolar hemorrhage (DAH) is a rare but fatal complication in patients with systemic lupus erythematosus (SLE). We describe a case of a 74-year-old woman who presented with DAH as an initial presentation of SLE. She also had microscopic polyangiitis clinically manifesting as crescentic glomerulonephritis and purpura with positive myeloperoxidase (MPO)-antineutrophil cytoplasmic antibodies (ANCA). The patient transiently improved when treated with plasma exchange and methylprednisolone pulse therapy; however, she died of recurrent pulmonary hemorrhage and concurrent cryptococcal pneumonia. This case indicates that MPO-ANCA is associated with severe organ involvement such as pulmonary hemorrhage and crescentic glomerulonephritis in SLE. Japanese Society of Nephrology, 2010 Diffuse alveolar hemorrhage nationallicence Lupus nephritis nationallicence MPO-ANCA nationallicence SLE nationallicence Isono Motohide Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Araki Hisazumi Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Haitani Takao Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Morita Yoshikata Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Yasuda Mako Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Kato Noriko Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Urasaki Koji Department of Pathology, Otsu Municipal Hospital, Otsu, Shiga, Japan aut Tsujimura Yoshinori Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut Clinical and Experimental Nephrology Springer Japan 15/2(2011-04-01), 294-298 1342-1751 15:2<294 2011 15 10157 https://doi.org/10.1007/s10157-010-0394-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10157-010-0394-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Isono Motohide Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Araki Hisazumi Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Haitani Takao Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Morita Yoshikata Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Yasuda Mako Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Kato Noriko Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Urasaki Koji Department of Pathology, Otsu Municipal Hospital, Otsu, Shiga, Japan aut NATIONALLICENCE 700 1- Tsujimura Yoshinori Department of Medicine, Otsu Municipal Hospital, 520-0804, Otsu, Shiga, Japan aut NATIONALLICENCE 773 0- Clinical and Experimental Nephrology Springer Japan 15/2(2011-04-01), 294-298 1342-1751 15:2<294 2011 15 10157 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer