caa a22 4500 445885653 CHVBK 20180317145558.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00011-010-0302-5 doi (NATIONALLICENCE)springer-10.1007/s00011-010-0302-5 Effect of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects and subjects with cardiovascular risk factors [Elektronische Daten] [Mari Myhrstad, Kjetil Retterstøl, Vibeke Telle-Hansen, Inger Ottestad, Bente Halvorsen, Kirsten Holven, Stine Ulven] Objective: The aim of the present paper was to review the literature in order to summarize the effects of marine n-3 fatty acids on circulating inflammatory markers among healthy subjects, subjects with high risk of developing cardiovascular disease (CVD) and in patients with CVD in human intervention studies. Methods: A systematic literature search in PubMed was performed. Intervention studies describing the effects of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects, subjects with high risk of CVD and patients with CVD were included. The following exclusion criteria were used: (1) interventions assessing inflammatory markers with ex vivo methods (2) interventions with children (3) articles describing animal or cell culture studies. Twenty-two articles were included. Additionally, 13 papers from their literature lists were included based on the same inclusion and exclusion criteria as the literature search. Results and conclusion: Intervention studies with marine n-3 fatty acids administered from either fish or fish oil demonstrate different results on inflammatory markers. No firm conclusion can be drawn about the effect of marine n-3 fatty acids on circulating inflammatory markers in healthy individuals, individuals with high risk of developing CVD or individuals with CVD related diseases. The Author(s), 2011 Omega-3 fatty acids nationallicence Atherosclerosis nationallicence Inflammation nationallicence Circulating inflammatory markers nationallicence PBMCs nationallicence Myhrstad Mari Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut Retterstøl Kjetil Lipid Clinic, Oslo University Hospital, Rikshospitalet, 0027, Oslo, Norway aut Telle-Hansen Vibeke Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut Ottestad Inger Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut Halvorsen Bente Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, 0027, Oslo, Norway aut Holven Kirsten Department of Nutrition, Institute of Basic Medical sciences, University of Oslo, PO Box 1046, 0316, Oslo, Blindern, Norway aut Ulven Stine Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut Inflammation Research SP Birkhäuser Verlag Basel 60/4(2011-04-01), 309-319 1023-3830 60:4<309 2011 60 11 https://doi.org/10.1007/s00011-010-0302-5 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00011-010-0302-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Myhrstad Mari Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut NATIONALLICENCE 700 1- Retterstøl Kjetil Lipid Clinic, Oslo University Hospital, Rikshospitalet, 0027, Oslo, Norway aut NATIONALLICENCE 700 1- Telle-Hansen Vibeke Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut NATIONALLICENCE 700 1- Ottestad Inger Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut NATIONALLICENCE 700 1- Halvorsen Bente Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, 0027, Oslo, Norway aut NATIONALLICENCE 700 1- Holven Kirsten Department of Nutrition, Institute of Basic Medical sciences, University of Oslo, PO Box 1046, 0316, Oslo, Blindern, Norway aut NATIONALLICENCE 700 1- Ulven Stine Faculty of Health, Nutrition and Management, Akershus University College, PO box 423, 2001, Lillestrøm, Norway aut NATIONALLICENCE 773 0- Inflammation Research SP Birkhäuser Verlag Basel 60/4(2011-04-01), 309-319 1023-3830 60:4<309 2011 60 11 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer