caa a22 4500 445887850 CHVBK 20180317145605.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00535-011-0399-5 doi (NATIONALLICENCE)springer-10.1007/s00535-011-0399-5 EUS elastography combined with the strain ratio of tissue elasticity for diagnosis of solid pancreatic masses [Elektronische Daten] [Fumihide Itokawa, Takao Itoi, Atsushi Sofuni, Toshio Kurihara, Takayoshi Tsuchiya, Kentaro Ishii, Shujiro Tsuji, Nobuhito Ikeuchi, Junko Umeda, Reina Tanaka, Naoyuki Yokoyama, Fuminori Moriyasu, Kazuhiko Kasuya, Toshitaka Nagao, Terumi Kamisawa, Akihiko Tsuchida] Background: Recently, the usefulness of endoscopic ultrasound (EUS) elastography has been reported for the diagnosis of pancreatic lesions. In the present study, we retrospectively assessed EUS elastography as a diagnostic tool by evaluating tissue elasticity distribution and elasticity semiquantification, using the strain ratio (SR) of tissue elasticity, in patients with pancreatic masses. Methods: One hundred and nine patients who underwent EUS elastography between September 2006 and May 2009 were retrospectively evaluated. The final diagnosis was chronic pancreatitis (CP) in 20 patients [6 with non-mass-forming pancreatitis, 7 with mass-forming pancreatitis (MFP), and 7 with autoimmune pancreatitis (AIP)], pancreatic cancer (PC) in 72, pancreatic neuroendocrine tumor (PNET) in 9, and normal pancreas in 8. The tissue elasticity distribution calculation was performed in real time, and the results were represented in color in fundamental B-mode imaging. In addition, we performed quantification using the SR (non-mass area/mass area). Results: Elastography for all PC patients showed intense blue coloration, indicating malignant lesions. In contrast, MFP presented with a mixed coloration pattern of green, yellow, and low-intensity blue. Normal controls showed an even distribution of green to red. The mean SR was 23.66±12.65 for MFP and 39.08±20.54 for PC (P<0.05). Conclusions: Endoscopic ultrasound elastography is a promising diagnostic tool for defining the tissue characteristics of pancreatic masses. In addition, semiquantitative analysis of elasticity using the SR may allow the differentiation of MFP from PC. Springer, 2011 Endoscopic ultrasound nationallicence Elastography nationallicence Pancreatic cancer nationallicence EUS : Endoscopic ultrasound nationallicence EUS-FNA : Endoscopic ultrasound fine-needle aspiration nationallicence SR : Strain ratio nationallicence CP : Chronic pancreatitis nationallicence MFP : Mass-forming pancreatitis nationallicence AIP : Autoimmune pancreatitis nationallicence PC : Pancreatic cancer nationallicence PNET : Pancreatic neuroendocrine tumor nationallicence Itokawa Fumihide Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Itoi Takao Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Sofuni Atsushi Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Kurihara Toshio Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Tsuchiya Takayoshi Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Ishii Kentaro Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Tsuji Shujiro Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Ikeuchi Nobuhito Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Umeda Junko Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Tanaka Reina Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Yokoyama Naoyuki Department of Clinical Oncology, Tokyo Medical University, Tokyo, Japan aut Moriyasu Fuminori Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut Kasuya Kazuhiko Third Department of Surgery, Tokyo Medical University, Tokyo, Japan aut Nagao Toshitaka Department of Pathology, Tokyo Medical University, Tokyo, Japan aut Kamisawa Terumi Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan aut Tsuchida Akihiko Third Department of Surgery, Tokyo Medical University, Tokyo, Japan aut Journal of Gastroenterology Springer Japan 46/6(2011-06-01), 843-853 0944-1174 46:6<843 2011 46 535 https://doi.org/10.1007/s00535-011-0399-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00535-011-0399-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Itokawa Fumihide Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Itoi Takao Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Sofuni Atsushi Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Kurihara Toshio Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsuchiya Takayoshi Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Ishii Kentaro Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsuji Shujiro Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Ikeuchi Nobuhito Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Umeda Junko Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Tanaka Reina Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Yokoyama Naoyuki Department of Clinical Oncology, Tokyo Medical University, Tokyo, Japan aut NATIONALLICENCE 700 1- Moriyasu Fuminori Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, 160-0023, Tokyo, Japan aut NATIONALLICENCE 700 1- Kasuya Kazuhiko Third Department of Surgery, Tokyo Medical University, Tokyo, Japan aut NATIONALLICENCE 700 1- Nagao Toshitaka Department of Pathology, Tokyo Medical University, Tokyo, Japan aut NATIONALLICENCE 700 1- Kamisawa Terumi Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsuchida Akihiko Third Department of Surgery, Tokyo Medical University, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Gastroenterology Springer Japan 46/6(2011-06-01), 843-853 0944-1174 46:6<843 2011 46 535 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer