caa a22 4500 445888172 CHVBK 20180317145606.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00535-011-0459-x doi (NATIONALLICENCE)springer-10.1007/s00535-011-0459-x Quantitative analysis of colorectal lesions observed on magnified endoscopy images [Elektronische Daten] [Keiichi Onji, Shigeto Yoshida, Shinji Tanaka, Rie Kawase, Yoshito Takemura, Shiro Oka, Toru Tamaki, Bisser Raytchev, Kazufumi Kaneda, Masaharu Yoshihara, Kazuaki Chayama] Background: Various surface mucosal pit patterns, as recognized by endoscopists, correlate with the histologic features of colorectal cancers. We investigated whether magnified endoscopy images of these pit patterns could be analyzed quantitatively and thus facilitate computer-aided diagnosis of colorectal lesions. Methods: We applied both texture analysis and scale-invariant feature transform (SIFT) descriptors and discriminant analysis to magnified endoscopy images of 165 neoplastic colorectal lesions (pit patterns: type IIIL/IV, n=44; type VI-mildly irregular, n=36; type VI-severely irregular, n=45; type VN, n=40) [histologic findings: tubular adenoma (TA), n=56; carcinoma with intramucosal or even scant submucosal invasion (M/SM-s), n=52, carcinoma with massive submucosal invasion (SM-m), n=57]. We analyzed differences in pit pattern values and corresponding histologic values to determine whether the values were diagnostically meaningful. Results: Gray-level difference matrix (GLDM) inverse difference moment and spatial gray-level dependence matrix (SGLDM) local homogeneity values differed significantly between type IIIL/IV and type VN pit patterns. Values differed significantly for each analyzed feature between type IIIL/IV and type VI-severely irregular patterns and were high but descending for type IIIL/IV, type VI-mildly irregular, and type VI-severely irregular pit patterns (in that order). Similarly, texture analysis yielded high but descending values for TA, M/SM-s, and SM-m (in that order). Furthermore, SIFT descriptors and discriminant analysis yielded differences that were superior to those obtained by texture analyses. Conclusions: Computer analysis of magnified endoscopy images for the diagnosis of colorectal lesions appears feasible. We anticipate further developments in the computer-aided diagnosis of pit patterns on magnified endoscopy images. Springer, 2011 Magnifying chromoendoscopy nationallicence Quantitative analysis nationallicence Image analysis nationallicence Colon cancer nationallicence Colonoscopy nationallicence Onji Keiichi Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Yoshida Shigeto Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Tanaka Shinji Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Kawase Rie Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Takemura Yoshito Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Oka Shiro Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Tamaki Toru Department of Information Engineering, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagami-yama, 739-8527, Hiroshima, Japan aut Raytchev Bisser Department of Information Engineering, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagami-yama, 739-8527, Hiroshima, Japan aut Kaneda Kazufumi Department of Information Engineering, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagami-yama, 739-8527, Hiroshima, Japan aut Yoshihara Masaharu Department of Health Service Center, Hiroshima University, 1-7-1 Kagami-yama, 739-8514, Hiroshima, Japan aut Chayama Kazuaki Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut Journal of Gastroenterology Springer Japan 46/12(2011-12-01), 1382-1390 0944-1174 46:12<1382 2011 46 535 https://doi.org/10.1007/s00535-011-0459-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00535-011-0459-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Onji Keiichi Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Yoshida Shigeto Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Tanaka Shinji Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Kawase Rie Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Takemura Yoshito Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Oka Shiro Department of Endoscopy, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Tamaki Toru Department of Information Engineering, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagami-yama, 739-8527, Hiroshima, Japan aut NATIONALLICENCE 700 1- Raytchev Bisser Department of Information Engineering, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagami-yama, 739-8527, Hiroshima, Japan aut NATIONALLICENCE 700 1- Kaneda Kazufumi Department of Information Engineering, Graduate School of Engineering, Hiroshima University, 1-4-1 Kagami-yama, 739-8527, Hiroshima, Japan aut NATIONALLICENCE 700 1- Yoshihara Masaharu Department of Health Service Center, Hiroshima University, 1-7-1 Kagami-yama, 739-8514, Hiroshima, Japan aut NATIONALLICENCE 700 1- Chayama Kazuaki Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 773 0- Journal of Gastroenterology Springer Japan 46/12(2011-12-01), 1382-1390 0944-1174 46:12<1382 2011 46 535 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer