caa a22 4500 445888245 CHVBK 20180317145606.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00535-011-0450-6 doi (NATIONALLICENCE)springer-10.1007/s00535-011-0450-6 Introduction of an examination and treatment for Helicobacter pylori infection in high school health screening [Elektronische Daten] [Taiji Akamatsu, Shinya Ichikawa, Sadahide Okudaira, Shuichi Yokosawa, Yugo Iwaya, Tomoaki Suga, Hiroyoshi Ota, Eiji Tanaka] Background: Recently, a significant relationship between gastric cancer and Helicobacter pylori infection has been proven. The purpose of this study was to elucidate the actual conditions of H. pylori infection in Japanese teenagers. Methods: The study subjects were students at a certain high school between 2007 and 2009. They were first examined with a urine-based enzyme-linked immunosorbent assay (ELISA) for detection of the antibody to H. pylori (RAPIRAN®). Students who tested positive on this screening examination visited Shinshu University Hospital and received esophagogastroduodenoscopy, and biopsy samples were taken to examine their H. pylori status. The resolution of H. pylori infection was assessed by urea breath test. Results: For 3years, 1,224 of 1,232 students (99.4%) received a screening examination for H. pylori infection. Sixty-four of these 1,224 students (5.2%) were found to be positive for H. pylori. Thirty of these 64 H. pylori-positive students visited our hospital, and 24 of them (80%) were confirmed to be infected by H. pylori. The most common endoscopic findings for students with H. pylori infection were nodular gastritis (58.3%) and closed-type atrophic gastritis (45.8%). Histological findings showed no evidence of intestinal metaplasia, except in one of the students. All 24 students were successfully cured of H. pylori infection. If this procedure were to be introduced into the nationwide health screening at Japanese high schools, we calculated that the cost of the prevention of a gastric cancer would be 454,073 yen for each person. Conclusions: The low rate of prevalence of H. pylori infection in Japanese teenagers would make it possible to perform examinations and carry out treatment for this infection in high school health screenings from the standpoint of medical economy. Springer, 2011 Helicobacter pylori nationallicence Health screening nationallicence High school nationallicence Gastric cancer nationallicence Cost-effectiveness nationallicence Akamatsu Taiji Endoscopy Center, Suzaka Hospital, Nagano Prefectural Hospital Organization, 1332 Suzaka, 382-0091, Suzaka, Nagano, Japan aut Ichikawa Shinya Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut Okudaira Sadahide Okudaira Clinic, Matsumoto, Japan aut Yokosawa Shuichi Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut Iwaya Yugo Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut Suga Tomoaki Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut Ota Hiroyoshi Department of Biomedical Sciences, School of Health Sciences, Shinshu University School of Medicine, Matsumoto, Japan aut Tanaka Eiji Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut Journal of Gastroenterology Springer Japan 46/12(2011-12-01), 1353-1360 0944-1174 46:12<1353 2011 46 535 https://doi.org/10.1007/s00535-011-0450-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00535-011-0450-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akamatsu Taiji Endoscopy Center, Suzaka Hospital, Nagano Prefectural Hospital Organization, 1332 Suzaka, 382-0091, Suzaka, Nagano, Japan aut NATIONALLICENCE 700 1- Ichikawa Shinya Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut NATIONALLICENCE 700 1- Okudaira Sadahide Okudaira Clinic, Matsumoto, Japan aut NATIONALLICENCE 700 1- Yokosawa Shuichi Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut NATIONALLICENCE 700 1- Iwaya Yugo Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut NATIONALLICENCE 700 1- Suga Tomoaki Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut NATIONALLICENCE 700 1- Ota Hiroyoshi Department of Biomedical Sciences, School of Health Sciences, Shinshu University School of Medicine, Matsumoto, Japan aut NATIONALLICENCE 700 1- Tanaka Eiji Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan aut NATIONALLICENCE 773 0- Journal of Gastroenterology Springer Japan 46/12(2011-12-01), 1353-1360 0944-1174 46:12<1353 2011 46 535 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer