caa a22 4500 44588889X CHVBK 20180317145609.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00535-011-0419-5 doi (NATIONALLICENCE)springer-10.1007/s00535-011-0419-5 Differences of image enhancement in image-enhanced endoscopy: narrow band imaging versus flexible spectral imaging color enhancement [Elektronische Daten] [Manabu Muto, Hirokazu Higuchi, Yasumasa Ezoe, Takahiro Horimatsu, Shuko Morita, Shin-ichi Miyamoto, Tsutomu Chiba] Background: Narrow band imaging (NBI) can emphasize images of the surface microvasculature of lesions, because the central wavelengths of the NBI filter are 415 and 540nm and these wavelengths are well absorbed by hemoglobin. Flexible spectral imaging color enhancement (FICE) increases the contrast in depictions of mucosal lesions. However, quantitative evaluation of the image enhancement shown by NBI and FICE has not been reported. The aim of this study was to measure and compare the degrees of image enhancement in NBI and FICE. Methods: We compared the visibility of human blood diluted with distilled water between that shown by white-light imaging (WLI) and that shown by NBI or FICE. One milliliter of human blood was plated onto a 12-well transparent plastic plate to set up doubling dilutions, from 1/2 to 1/223. High-definition endoscopes were used for each imaging method. A total of 11 endoscopists independently evaluated the visibility of the diluted blood. The median dilution was defined as the limit of visibility in each image. Results: NBI enabled clearer visualization of the presence of blood compared with conventional WLI. NBI recognized blood contamination up to a 1/214 dilution, whereas conventional WLI recognized blood contamination up to a 1/211 dilution. In contrast, FICE did not improve the visualization of diluted blood and recognized blood contamination up to a 1/210 dilution. Conclusions: NBI more effectively enhanced images of diluted blood compared to conventional WLI, while FICE did not improve the visualization of the diluted blood. These data suggest the usefulness of NBI for the early detection of gastrointestinal neoplasia, which is accompanied by abundant neovascularization. Springer, 2011 Image-enhanced endoscopy nationallicence Narrow band imaging nationallicence Flexible spectral imaging color enhancement nationallicence Muto Manabu Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Higuchi Hirokazu Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Ezoe Yasumasa Department of Multidisciplinary Cancer Treatment, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Horimatsu Takahiro Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Morita Shuko Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Miyamoto Shin-ichi Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Chiba Tsutomu Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut Journal of Gastroenterology Springer Japan 46/8(2011-08-01), 998-1002 0944-1174 46:8<998 2011 46 535 https://doi.org/10.1007/s00535-011-0419-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00535-011-0419-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Muto Manabu Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 700 1- Higuchi Hirokazu Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 700 1- Ezoe Yasumasa Department of Multidisciplinary Cancer Treatment, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 700 1- Horimatsu Takahiro Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 700 1- Morita Shuko Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 700 1- Miyamoto Shin-ichi Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 700 1- Chiba Tsutomu Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 54 Kawahara Cho, Syogoin, Sakyo-ku, 606-8507, Kyoto, Japan aut NATIONALLICENCE 773 0- Journal of Gastroenterology Springer Japan 46/8(2011-08-01), 998-1002 0944-1174 46:8<998 2011 46 535 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer