caa a22 4500 445889144 CHVBK 20180317145610.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00535-010-0298-1 doi (NATIONALLICENCE)springer-10.1007/s00535-010-0298-1 Endoscopic nasobiliary drainage is the most suitable preoperative biliary drainage method in the management of patients with hilar cholangiocarcinoma [Elektronische Daten] [Hiroshi Kawakami, Masaki Kuwatani, Manabu Onodera, Shin Haba, Kazunori Eto, Nobuyuki Ehira, Hiroaki Yamato, Taiki Kudo, Eiichi Tanaka, Satoshi Hirano, Satoshi Kondo, Masahiro Asaka] Background: Controversy exists over the preferred technique of preoperative biliary drainage (PBD) in patients with hilar cholangiocarcinoma (HCA). The goal of this retrospective study was to identify the preferred technique of PBD for HCA. Methods: A total of 128 consecutive patients with HCA diagnosed between September 1999 and December 2009 who underwent PBD were included in this study. The study compared outcomes of endoscopic nasobiliary drainage (ENBD), endoscopic biliary stenting (EBS), and percutaneous transhepatic biliary drainage (PTBD) in patients with HCA. Results: There were no significant differences in preoperative laboratory data, rates of major hepatectomy, or decompression periods among the 3 groups. Complications were significantly more frequent in the EBS group compared with either the ENBD or PTBD group (p<0.05). Drainage tube occlusion with cholangitis was significantly more common in the EBS group compared with either the ENBD or PTBD group (p<0.0001). Patients in the PTBD group experienced serious complications including vascular injury (8%) and cancer dissemination (4%). Patients in the ENBD and EBS groups had mild post-endoscopic retrograde cholangiopancreatography pancreatitis (5%). Conversion procedures were significantly more common in the EBS group compared with the ENBD and PTBD groups (p<0.05). There was no significant difference in postsurgical morbidity or mortality among the 3 groups. Conclusions: Drainage tube occlusion with cholangitis was a frequent complication associated with EBS. PTBD was associated with serious complications such as vascular injury and cancer dissemination. ENBD was found to be the most suitable method for initial PBD management in patients with HCA. Springer, 2010 Hilar cholangiocarcinoma nationallicence Preoperative biliary drainage nationallicence Endoscopic biliary drainage nationallicence Endoscopic nasobiliary drainage nationallicence Percutaneous transhepatic biliary drainage nationallicence PTBD : Percutaneous transhepatic biliary drainage nationallicence PBD : Preoperative biliary drainage nationallicence ENBD : Endoscopic nasobiliary drainage nationallicence EBS : Endoscopic biliary stenting nationallicence ERCP : Endoscopic retrograde cholangiopancreatography nationallicence ICG : Indocyanine green nationallicence EBD : Endoscopic biliary drainage nationallicence EST : Endoscopic sphincterotomy nationallicence HCA : Hilar cholangiocarcinoma nationallicence Kawakami Hiroshi Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Kuwatani Masaki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Onodera Manabu Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Haba Shin Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Eto Kazunori Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Ehira Nobuyuki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Yamato Hiroaki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Kudo Taiki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Tanaka Eiichi Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut Hirano Satoshi Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut Kondo Satoshi Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut Asaka Masahiro Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut Journal of Gastroenterology Springer Japan 46/2(2011-02-01), 242-248 0944-1174 46:2<242 2011 46 535 https://doi.org/10.1007/s00535-010-0298-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00535-010-0298-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kawakami Hiroshi Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Kuwatani Masaki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Onodera Manabu Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Haba Shin Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Eto Kazunori Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Ehira Nobuyuki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Yamato Hiroaki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Kudo Taiki Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Tanaka Eiichi Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Hirano Satoshi Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Kondo Satoshi Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Asaka Masahiro Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 773 0- Journal of Gastroenterology Springer Japan 46/2(2011-02-01), 242-248 0944-1174 46:2<242 2011 46 535 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer