caa a22 4500 445889764 CHVBK 20180317145612.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s11120-011-9631-7 doi (NATIONALLICENCE)springer-10.1007/s11120-011-9631-7 A new dawn for industrial photosynthesis [Elektronische Daten] [Dan Robertson, Stuart Jacobson, Frederick Morgan, David Berry, George Church, Noubar Afeyan] Several emerging technologies are aiming to meet renewable fuel standards, mitigate greenhouse gas emissions, and provide viable alternatives to fossil fuels. Direct conversion of solar energy into fungible liquid fuel is a particularly attractive option, though conversion of that energy on an industrial scale depends on the efficiency of its capture and conversion. Large-scale programs have been undertaken in the recent past that used solar energy to grow innately oil-producing algae for biomass processing to biodiesel fuel. These efforts were ultimately deemed to be uneconomical because the costs of culturing, harvesting, and processing of algal biomass were not balanced by the process efficiencies for solar photon capture and conversion. This analysis addresses solar capture and conversion efficiencies and introduces a unique systems approach, enabled by advances in strain engineering, photobioreactor design, and a process that contradicts prejudicial opinions about the viability of industrial photosynthesis. We calculate efficiencies for this direct, continuous solar process based on common boundary conditions, empirical measurements and validated assumptions wherein genetically engineered cyanobacteria convert industrially sourced, high-concentration CO2 into secreted, fungible hydrocarbon products in a continuous process. These innovations are projected to operate at areal productivities far exceeding those based on accumulation and refining of plant or algal biomass or on prior assumptions of photosynthetic productivity. This concept, currently enabled for production of ethanol and alkane diesel fuel molecules, and operating at pilot scale, establishes a new paradigm for high productivity manufacturing of nonfossil-derived fuels and chemicals. The Author(s), 2011 Cyanobacteria nationallicence Metabolic engineering nationallicence Hydrocarbon nationallicence Alkane nationallicence Diesel nationallicence Renewable fuel nationallicence Algae nationallicence Biomass nationallicence Biodiesel nationallicence Robertson Dan Biological Sciences, Joule Unlimited, 83 Rogers Street, 02142, Cambridge, MA, USA aut Jacobson Stuart Engineering, Joule Unlimited, 83 Rogers Street, 02142, Cambridge, MA, USA aut Morgan Frederick Engineering, Joule Unlimited, 83 Rogers Street, 02142, Cambridge, MA, USA aut Berry David Flagship VentureLabs, 1 Memorial Drive, 02142, Cambridge, MA, USA aut Church George Department of Genetics, Harvard University, School of Medicine, 77 Ave Louis Pasteur, NRB 238, 02115, Boston, MA, USA aut Afeyan Noubar Flagship VentureLabs, 1 Memorial Drive, 02142, Cambridge, MA, USA aut Photosynthesis Research Springer Netherlands 107/3(2011-03-01), 269-277 0166-8595 107:3<269 2011 107 11120 https://doi.org/10.1007/s11120-011-9631-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11120-011-9631-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Robertson Dan Biological Sciences, Joule Unlimited, 83 Rogers Street, 02142, Cambridge, MA, USA aut NATIONALLICENCE 700 1- Jacobson Stuart Engineering, Joule Unlimited, 83 Rogers Street, 02142, Cambridge, MA, USA aut NATIONALLICENCE 700 1- Morgan Frederick Engineering, Joule Unlimited, 83 Rogers Street, 02142, Cambridge, MA, USA aut NATIONALLICENCE 700 1- Berry David Flagship VentureLabs, 1 Memorial Drive, 02142, Cambridge, MA, USA aut NATIONALLICENCE 700 1- Church George Department of Genetics, Harvard University, School of Medicine, 77 Ave Louis Pasteur, NRB 238, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Afeyan Noubar Flagship VentureLabs, 1 Memorial Drive, 02142, Cambridge, MA, USA aut NATIONALLICENCE 773 0- Photosynthesis Research Springer Netherlands 107/3(2011-03-01), 269-277 0166-8595 107:3<269 2011 107 11120 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer