caa a22 4500 445892552 CHVBK 20180317145621.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s10750-010-0489-z doi (NATIONALLICENCE)springer-10.1007/s10750-010-0489-z The role of serotonin in a bdelloid life cycle [Elektronische Daten] [Francesca Leasi, Claudia Ricci] Serotonin is a neurotransmitter present throughout animal kingdom that controls a number of crucial functions in different taxa. In this study we document the role of serotonin in a bdelloid rotifer, Macrotrachela quadricornifera. Following life table experimental protocol, we recorded age-specific fecundity and survival rates of cohorts that received WAY 100135 maleate, a selective antagonist of the serotonin receptor 1A. The antagonist was provided from the age of 4days (age at first reproduction) until death to one cohort group, and during 15days to another group. Both groups were cultivated regularly, and their life history traits were recorded. Treated rotifers continued to produce eggs, but most eggs were never oviposited and eventually ruptured the mother's body wall. The retained eggs, being parthenogenetic began embryogenesis and some could hatch inside the mother's body cavity (pseudocoel). When WAY was suspended, most treated rotifers oviposited all their eggs. About 75% of these eggs developed, but development was 1-2days longer than in controls. Most newborns reached sexual maturity, although their maturity was delayed as well. Eggs produced after WAY suspension hatched as much as the controls (~100%). WAY possibly did not affect egg production, but prevented regular oviposition. Nevertheless, viability was reduced and development took longer during WAY treatment. Results suggest that in bdelloid rotifers serotonin is involved in the control of egg laying and development, among other features, as it does in most animals, from nematodes to chordates. Springer Science+Business Media B.V., 2010 5-HT1A receptor nationallicence WAY 100135 maleate nationallicence Macrotrachela quadricornifera nationallicence Egg laying nationallicence Development nationallicence Leasi Francesca Department of Biology, University of Milan, Via Celoria 26, 20133, Milan, Italy aut Ricci Claudia DIPSA (Protezione dei Sistemi Agroalimentare e Urbano e Valorizzazione delle Biodiversità), University of Milan, Via Celoria 2, 20133, Milan, Italy aut Hydrobiologia Springer Netherlands 662/1(2011-03-01), 141-147 0018-8158 662:1<141 2011 662 10750 https://doi.org/10.1007/s10750-010-0489-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10750-010-0489-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Leasi Francesca Department of Biology, University of Milan, Via Celoria 26, 20133, Milan, Italy aut NATIONALLICENCE 700 1- Ricci Claudia DIPSA (Protezione dei Sistemi Agroalimentare e Urbano e Valorizzazione delle Biodiversità), University of Milan, Via Celoria 2, 20133, Milan, Italy aut NATIONALLICENCE 773 0- Hydrobiologia Springer Netherlands 662/1(2011-03-01), 141-147 0018-8158 662:1<141 2011 662 10750 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer