caa a22 4500 463157516 CHVBK 20180406164738.0 cr unu---uuuuu 170326e20070201xx s 000 0 eng 10.1007/s00217-006-0400-3 doi (NATIONALLICENCE)springer-10.1007/s00217-006-0400-3 Phytochemical and biological investigation of Stevia rebaudiana Bertoni; 1-labdane-type diterpene [Elektronische Daten] [Nabaweya Ibrahim, Souad El-Gengaihi, H. Motawe, S. Riad] Five labdane diterpenoids, austroinulin, iso-austroinulin, sterebin E, sterebin E acetate, and sterebin A acetate, along with hydrocarbons, aliphatic alcohols, β-amyrin, β-sitosterol and stigmasterol were isolated from the chloroform soluble fraction of the methanol extract of Stevia rebaudiana leaves. Chlorogenic and caffeic acids were isolated from the EtOAc fraction. All the isolated compounds were identified using spectral tools. The chloroform and methanol extracts proved significant anti-inflammatory effect and caused marked inhibition of carrageenan-induced paw oedema in rats. Springer-Verlag, 2006 Stevia rebaudiana nationallicence Labdane diterpenes nationallicence Chlorogenic acid nationallicence Caffeic acid nationallicence Anti-inflammatory nationallicence Ibrahim Nabaweya Pharmacognosy Department, National Research Center, Dokki, Cairo, Egypt aut El-Gengaihi Souad Medicinal and Aromatic Plants Department, National Research Center, Dokki, Cairo, Egypt aut Motawe H. Pharmacognosy Department, National Research Center, Dokki, Cairo, Egypt aut Riad S. Medicinal and Aromatic Plants Department, National Research Center, Dokki, Cairo, Egypt aut European Food Research and Technology Springer-Verlag 224/4(2007-02-01), 483-488 1438-2377 224:4<483 2007 224 217 https://doi.org/10.1007/s00217-006-0400-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00217-006-0400-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ibrahim Nabaweya Pharmacognosy Department, National Research Center, Dokki, Cairo, Egypt aut NATIONALLICENCE 700 1- El-Gengaihi Souad Medicinal and Aromatic Plants Department, National Research Center, Dokki, Cairo, Egypt aut NATIONALLICENCE 700 1- Motawe H. Pharmacognosy Department, National Research Center, Dokki, Cairo, Egypt aut NATIONALLICENCE 700 1- Riad S. Medicinal and Aromatic Plants Department, National Research Center, Dokki, Cairo, Egypt aut NATIONALLICENCE 773 0- European Food Research and Technology Springer-Verlag 224/4(2007-02-01), 483-488 1438-2377 224:4<483 2007 224 217 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer