caa a22 4500 463157923 CHVBK 20180406164739.0 cr unu---uuuuu 170326e20071201xx s 000 0 eng 10.1007/s10286-007-0446-8 doi (NATIONALLICENCE)springer-10.1007/s10286-007-0446-8 Skin autonomic reactivity to thermoalgesic stimuli [Elektronische Daten] [Pedro Schestatsky, Josep Valls-Solé, João Costa, Lucia León, Misericordia Veciana, Márcia Chaves] Objective: Quantitative sensory testing (QST) is a subjective method of assessing thermal sensation, but it does not provide an objective measure of physiological changes. Our aim was to establish whether fluctuations in sudomotor autonomic activity correlate with warmth and heat pain (thermoalgesic) perception. Methods: We conducted various thermal stimuli protocols in 22 healthy volunteers and recorded the visual analog scale (VAS) and sudomotor activity using surface electrodes attached to the hand. Sympathetic skin responses (SSR) and the mean level of electrodermal activity (EDA) were measured. EDA was analyzed by looking at the four VAS-based phases, which were divided into segments defined by the relevant psychophysical markers. Results: In all stimuli paradigms, the mean delay time of the SSR was 1.6s after the warmth or pain sensation. There was an association between the low amplitude (predominantly negative) SSR and warm stimuli, and the large amplitude (predominantly positive) SSR and heat pain stimuli (chi-square; P<0.05). Mean EDA was significantly higher during the pain phase in comparison with pre-perception, warmth and post-perception phases. Intepretation: Thermoalgesic stimuli induce reflex changes in sudomotor activity that correlate with subjective perception of warmth and heat pain sensations. This association may be useful in clinical practice. Springer, 2007 quantitative sensory testing nationallicence sympathetic skin response nationallicence pain nationallicence psychophysics nationallicence autonomic nervous system nationallicence Schestatsky Pedro Medical Sciences Post-Graduation Course, UFRGS School of Medicine, Porto Alegre, Brazil aut Valls-Solé Josep Dept. of Neurology, EMG Unit, Hospital Clínic, Universitat de Barcelona, Villarroel, 170, 08036, Barcelona, Spain aut Costa João Dept. of Neurology, Faculty of Medicine, Hospital Santa Maria, Lisbon, Portugal aut León Lucia Dept. of Neurology, EMG Unit, Hospital Clínic, Universitat de Barcelona, Villarroel, 170, 08036, Barcelona, Spain aut Veciana Misericordia Dept. of Neurology, Hospital de Sant Boi, Barcelona, Spain aut Chaves Márcia Medical Sciences Post-Graduation Course, UFRGS School of Medicine, Porto Alegre, Brazil aut https://doi.org/10.1007/s10286-007-0446-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10286-007-0446-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schestatsky Pedro Medical Sciences Post-Graduation Course, UFRGS School of Medicine, Porto Alegre, Brazil aut NATIONALLICENCE 700 1- Valls-Solé Josep Dept. of Neurology, EMG Unit, Hospital Clínic, Universitat de Barcelona, Villarroel, 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Costa João Dept. of Neurology, Faculty of Medicine, Hospital Santa Maria, Lisbon, Portugal aut NATIONALLICENCE 700 1- León Lucia Dept. of Neurology, EMG Unit, Hospital Clínic, Universitat de Barcelona, Villarroel, 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Veciana Misericordia Dept. of Neurology, Hospital de Sant Boi, Barcelona, Spain aut NATIONALLICENCE 700 1- Chaves Márcia Medical Sciences Post-Graduation Course, UFRGS School of Medicine, Porto Alegre, Brazil aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer