caa a22 4500 463170393 CHVBK 20180406164811.0 cr unu---uuuuu 170326e20070201xx s 000 0 eng 10.1007/s10450-007-9008-6 doi (NATIONALLICENCE)springer-10.1007/s10450-007-9008-6 Experimental investigation of liquid chromatography columns by means of computed tomography [Elektronische Daten] [Dirk-Uwe Astrath, Florian Lottes, Duc Vu, Wolfgang Arlt, Erling Stenby] The efficiency of packed chromatographic columns was investigated experimentally by means of computed tomography (CT) techniques. The measurements were carried out by monitoring tracer fronts in situ inside the chromatographic columns. The experimental results were fitted using the equilibrium dispersive model (EDM) and varying the so called apparent axial dispersion coefficient. The additivity of the first and second central moments was exploited to estimate column efficiency in different regions of the column. The results showed that the columns under investigation offered a higher column efficiency in the centre compared to the wall region. Furthermore the void fraction in the vicinity of the walls was lower than that in the column core. For this reason the bands were conveyed faster in the central region of the column where the permeability was higher. This result is in good agreement with earlier findings. Springer Science+Business Media, LLC, 2007 Chromatography nationallicence Computed tomography (CT) nationallicence Astrath Dirk-Uwe Lehrstuhl für Thermische Verfahrenstechnik, Institut für Chemie- und Bioingenieurwesen, Friedrich-Alexander University Erlangen-Nuremberg, Egerlandstr. 3, 91058, Erlangen, Germany aut Lottes Florian Lehrstuhl für Thermische Verfahrenstechnik, Institut für Chemie- und Bioingenieurwesen, Friedrich-Alexander University Erlangen-Nuremberg, Egerlandstr. 3, 91058, Erlangen, Germany aut Vu Duc Engineering Research Center—Phase Equilibria and Separation Processes (IVC-SEP), Department of Chemical Engineering, Technical University of Denmark, Building 229, 2800, Lyngby, Denmark aut Arlt Wolfgang Lehrstuhl für Thermische Verfahrenstechnik, Institut für Chemie- und Bioingenieurwesen, Friedrich-Alexander University Erlangen-Nuremberg, Egerlandstr. 3, 91058, Erlangen, Germany aut Stenby Erling Engineering Research Center—Phase Equilibria and Separation Processes (IVC-SEP), Department of Chemical Engineering, Technical University of Denmark, Building 229, 2800, Lyngby, Denmark aut Adsorption Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 13/1(2007-02-01), 9-19 0929-5607 13:1<9 2007 13 10450 https://doi.org/10.1007/s10450-007-9008-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10450-007-9008-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Astrath Dirk-Uwe Lehrstuhl für Thermische Verfahrenstechnik, Institut für Chemie- und Bioingenieurwesen, Friedrich-Alexander University Erlangen-Nuremberg, Egerlandstr. 3, 91058, Erlangen, Germany aut NATIONALLICENCE 700 1- Lottes Florian Lehrstuhl für Thermische Verfahrenstechnik, Institut für Chemie- und Bioingenieurwesen, Friedrich-Alexander University Erlangen-Nuremberg, Egerlandstr. 3, 91058, Erlangen, Germany aut NATIONALLICENCE 700 1- Vu Duc Engineering Research Center—Phase Equilibria and Separation Processes (IVC-SEP), Department of Chemical Engineering, Technical University of Denmark, Building 229, 2800, Lyngby, Denmark aut NATIONALLICENCE 700 1- Arlt Wolfgang Lehrstuhl für Thermische Verfahrenstechnik, Institut für Chemie- und Bioingenieurwesen, Friedrich-Alexander University Erlangen-Nuremberg, Egerlandstr. 3, 91058, Erlangen, Germany aut NATIONALLICENCE 700 1- Stenby Erling Engineering Research Center—Phase Equilibria and Separation Processes (IVC-SEP), Department of Chemical Engineering, Technical University of Denmark, Building 229, 2800, Lyngby, Denmark aut NATIONALLICENCE 773 0- Adsorption Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 13/1(2007-02-01), 9-19 0929-5607 13:1<9 2007 13 10450 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer