caa a22 4500 463175751 CHVBK 20180406164825.0 cr unu---uuuuu 170326e20071201xx s 000 0 eng 10.1007/s10336-007-0230-5 doi (NATIONALLICENCE)springer-10.1007/s10336-007-0230-5 Westerdahl Helena Department of Animal Ecology, Ecology Building, Lund University, 223 62, Lund, Sweden aut Passerine MHC: genetic variation and disease resistance in the wild [Elektronische Daten] [Helena Westerdahl] The passerine major histocompatibility complex (MHC) class I and IIB genes are different from those of the avian model species the chicken because passerines have (1) a larger number of MHC genes, (2) MHC genes with longer introns, and (3) MHC genes that are pseudogenes. Most passerine MHC genes are transcribed (coding), extremely variable and subject to balancing selection. The high genetic diversity of the MHC genes of passerines is most likely maintained by selection from a large number of different pathogens. Association between MHC alleles and resistance to avian malaria infections have been reported in House Sparrows and Great Reed Warblers. Passerines are infected by a large number of different avian malaria infections. Therefore passerines and avian malaria is a study system that is well-suited to investigations of balancing selection and associations between MHC genes and disease resistance. Dt. Ornithologen-Gesellschaft e.V., 2007 Passerines nationallicence MHC class I and class II nationallicence Balancing selection nationallicence Avian malaria nationallicence Disease resistance nationallicence Journal of Ornithology Springer-Verlag 148(2007-12-01), 469-477 0021-8375 148<469 2007 148 10336 https://doi.org/10.1007/s10336-007-0230-5 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10336-007-0230-5 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Westerdahl Helena Department of Animal Ecology, Ecology Building, Lund University, 223 62, Lund, Sweden aut NATIONALLICENCE 773 0- Journal of Ornithology Springer-Verlag 148(2007-12-01), 469-477 0021-8375 148<469 2007 148 10336 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer